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MABT75 Anti-Titin (NT/Z-domain) Antibody, clone 17D11.1

Anti-Titin (N-terminal/Z-domain) Antibody, clone 17D11.1 is an antibody against Titin (N-terminal/Z-domain) for use in Western Blotting, IHC(P).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Cytoskeleton Gene Symbol: TTN UniProt Number: Q8WZ42
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MABT75
100 µg  
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      Overview

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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABT75
      DescriptionAnti-Titin (NT/Z-domain) Antibody, clone 17D11.1
      Alternate Names
      • Titin
      • Connectin
      • Rhabdomyosarcoma antigen MU-RMS-40.14
      Background InformationTitin is a large complex protein containing over one hundred IgG-like and fibronectin type-III domains, in addition to multiple Kelch, RCC1, TPR, and WD repeats. It is a member of the CAMK Ser/Thr protein kinase family and also possesses a protein kinase domain, which is involved in controlling gene expression and protein turnover in muscle tissues. Titin also functions as a sensor to mediate appropriate cellular responses to mechanical stress. In striated muscle tissue, titin regulates the length of the sarcomere by integrating myosin and actin filaments at the Z-disk and M-band, and facilitates the elasticity of the sarcomere. Titin also regulates sarcomere assembly and functions as central hub in signal transduction pathways. Defects in Titin may contribute to various forms of cardiomyopathy.
      References
      Product Information
      FormatPurified
      Control
      • Human and mouse cardiac muscle tissues
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Titin (N-terminal/Z-domain) Antibody, clone 17D11.1 is an antibody against Titin (N-terminal/Z-domain) for use in Western Blotting, IHC(P).
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Titin.
      Clone17D11.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TTN
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight38 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in human and mouse cardiac muscle tissues.

      Immunohistochemistry Analysis: 1:1,000 dilution of this antibody detected Titin in human and mouse cardiac muscle tissues.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      MABT75 04053252646331

      Documentation

      Anti-Titin (NT/Z-domain) Antibody, clone 17D11.1 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Titin (NT/Z-domain) Antibody, clone 17D11.1 Certificates of Analysis

      TitleLot Number
      Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 2433594 2433594
      Anti-Titin (N-terminal/Z-domain), -2724172 2724172
      Anti-Titin (N-terminal/Z-domain), -2774076 2774076
      Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3311782 3311782
      Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3386473 3386473
      Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3736709 3736709
      Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3880435 3880435
      Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3899582 3899582
      Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - Q2015738 Q2015738
      Anti-Titin (N-terminal/Z-domain), clone 17D11.1 Monoclonal Antibody 3134088
      Show more

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies