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ABS796 Anti-phospho-HER4 Antibody (Tyr1162)

Detect HER4 using this rabbit polyclonal Anti-phospho-HER4 Antibody, Cat. No. ABS796, validated for use in Western Blotting, Immunohistochemistry, and Immunocytochemistry.

Anti-phospho-HER4 Antibody (Tyr1162) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: General Post-translation Modification Gene Symbol: ERBB4 UniProt Number: Q15303
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ABS796
80 µL  
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      Overview

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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHC, ICCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS796
      DescriptionAnti-phospho-HER4 Antibody (Tyr1162)
      Alternate Names
      • ERBB4
      • HER4
      • Receptor tyrosine-protein kinase erbB-4
      • Proto-oncogene-like protein c-ErbB-4
      • Tyrosine kinase-type cell surface receptor HER4
      • p180erbB4
      • ERBB4 intracellular domain
      • s80HER4
      Background InformationReceptor tyrosine-protein kinase erbB-4, also known as, Proto-oncogene-like protein c-ErbB-4 (4ICD or E4ICD), and encoded by the gene names Erbb4 or Tyro-2, plays an essential role as cell surface receptor for neuregulins. ERBB4 regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. ERBB4 is preferentially expressed in the developing nervous system. It exhibits distinct and highly regionalized patterns of expression in the adult brain, where it is mainly found in the reticular nucleus of the thalamus.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS with 0.09% (W/V) sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect HER4 using this rabbit polyclonal Anti-phospho-HER4 Antibody, Cat. No. ABS796, validated for use in Western Blotting, Immunohistochemistry, and Immunocytochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Immunocytochemistry
      Application NotesImmunohistochemistry Analysis (IHC): A 1:10-50 dilution from a representative lot detected HER4 in human cancer tissue.

      Immunocytochemistry Analysis (ICC): A 1:10-50 dilution from a representative lot detected HER4 in MCF-7 cells.
      Biological Information
      ImmunogenKLH-conjugated synthetic peptide corresponding to human PGK1 phosphorylated at Tyr1162.
      EpitopePhosphorylated Tyr1162
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • ERBB4
      Modifications
      • Phosphorylation
      Purification MethodAffinity
      UniProt Number
      Molecular Weight~160 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in untreated and EGF treated A431 cell lysates.

      Western Blotting Analysis (WB): A 1:1000 dilution of this antibody detected HER4 in untreated and EGF treated A431 cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size80 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      ABS796 04055977157208

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies