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GF320 CD40 Ligand, Human Recombinant
Animal Free

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P29965
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GF320
50µg  
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      Overview

      Replacement Information

      Key Specifications Table

      SourcePurity
      Protein is expressed in E.coli.
      The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.      		Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
      Description
      Catalogue NumberGF320
      DescriptionCD40 Ligand, Human Recombinant
      Animal Free
      Alternate Names
      • CD154
      • CD40 LIGAND
      • CD40L
      • GP39
      • hCD40L
      Background InformationCD40, a member of the TNF receptor superfamily, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to “immunodeficiency with hyper-IgM”, a disease characterized by failure to produce IgG, IgA and IgE.
      Recombinant human soluble CD40 ligand is a 16.3 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L.
      References
      Product Information
      PresentationProduct is presented in 10mM Sodium Phosphate, pH 7.5 and is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ100
      Applications
      Biological Information
      PurityProduct endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
      SourceProtein is expressed in E.coli.
      The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceBioactivity assay:
      Determined by its ability to stimulate the proliferation of HEK-BlueTM CD40 reporter cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
      Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
      Packaging Information
      Material Size50µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      GF320 04053252979606

      Documentation

      CD40 Ligand, Human Recombinant
      Animal Free SDS

      Title

      Safety Data Sheet (SDS) 

      CD40 Ligand, Human Recombinant
      Animal Free Certificates of Analysis

      TitleLot Number
      CD40 Ligand, Human Recombinant Animal Free - Q2441379 Q2441379
      CD40 Ligand, Human Recombinant - 3194587 3194587
      CD40 Ligand, Human Recombinant -2803639 2803639
      CD40 Ligand, Human Recombinant Animal Free - 3197624 3197624
      CD40 Ligand, Human Recombinant Animal Free - 3442489 3442489
      CD40 Ligand, Human Recombinant Animal Free - 3463554 3463554
      CD40 Ligand, Human Recombinant Animal Free - 3928096 3928096
      CD40 Ligand, Human Recombinant Animal Free - 4119027 4119027
      CD40 Ligand, Human Recombinant Animal Free Recombinant Protein 2984164
      CD40 Ligand, Human Recombinant Animal Free Recombinant Protein 2898241

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