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220201 MilliporeCHAPS, Molecular Biology Grade - CAS 75621-03-3 - Calbiochem

CAS 75621-03-3 is a zwitterionic detergent that combines features of bile salts and N-alkyl sulfobetaines.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

SDS
CoA
References
Brochures
Data Sheet

Synonyms: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

Recommended Products

Overview

Replacement Information

Key Specifications Table

CAS #	Empirical Formula
75621-03-3	C₃₂H₅₈N₂O₇S

Pricing & Availability

Catalog Number	Availability	Packaging	Qty/Pack	Price	Quantity
220201-10GM	Retrieving availability... — Limited Availability Stocked Discontinued Limited Quantities Available Available Login to See Inventory Stocked Limited Availability Stocked Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Plastic bottle	10 gm	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
220201-1GM	Retrieving availability... — Limited Availability Stocked Discontinued Limited Quantities Available Available Login to See Inventory Stocked Limited Availability Stocked Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Plastic bottle	1 gm	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
220201-1KG	Retrieving availability... — Limited Availability Stocked Discontinued Limited Quantities Available Available Login to See Inventory Stocked Limited Availability Stocked Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Plastic bottle	1 kg	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
220201-250GM	Retrieving availability... — Limited Availability Stocked Discontinued Limited Quantities Available Available Login to See Inventory Stocked Limited Availability Stocked Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Plastic bottle	250 gm	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
220201-25GM	Retrieving availability... — Limited Availability Stocked Discontinued Limited Quantities Available Available Login to See Inventory Stocked Limited Availability Stocked Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Plastic bottle	25 gm	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
220201-5GM	Retrieving availability... — Limited Availability Stocked Discontinued Limited Quantities Available Available Login to See Inventory Stocked Limited Availability Stocked Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Plastic bottle	5 gm	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites

Description
Overview	Zwitterionic detergent that combines features of bile salts and N-alkyl sulfobetaines. Better at solubilizing proteins than structurally-related carboxylic acid anions and is much more effective at breaking protein-protein interactions than either sodium cholate or TRITON^® X-100 Detergent. Capable of solubilizing the opiate receptor to a state exhibiting reversible binding of opiates. Also, capable of disaggregating cytochrome P450 to its monomeric form without denaturation. Has a small micellar molecular weight and a high critical micellar concentration and can be removed from either gels or protein solutions by dialysis across a membrane. Aggregation number: 4-14.
Overview	Conductivity (1.0 M, 24°C): <100 µmhos.
Catalogue Number	220201
Brand Family	Calbiochem®
Synonyms	3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

References
References	Chen, Y., et al. 1992. Biochemistry 31, 2415. Ofri, D., et al. 1992. J. Neurochem. 58, 628. Ransom, R.W., et al. 1992. Biochem. Pharmacol. 43, 1823. Simonds, W.F., et al. 1992. Proc. Natl. Acad. Sci. USA 77, 4623. Yannariello-Brown, J., and Weigel, P.H. 1992. Biochemistry 31, 576. Hjelmeland, L.M. 1980. Proc. Natl. Acad. Sci. USA 77, 6368. Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 4623.

References

Chen, Y., et al. 1992. Biochemistry 31, 2415.
Ofri, D., et al. 1992. J. Neurochem. 58, 628.
Ransom, R.W., et al. 1992. Biochem. Pharmacol. 43, 1823.
Simonds, W.F., et al. 1992. Proc. Natl. Acad. Sci. USA 77, 4623.
Yannariello-Brown, J., and Weigel, P.H. 1992. Biochemistry 31, 576.
Hjelmeland, L.M. 1980. Proc. Natl. Acad. Sci. USA 77, 6368.
Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 4623.

Product Information
CAS number	75621-03-3
Aggregation Number	4 - 14
CMC	6 - 10 mM
Form	White crystalline powder
Hill Formula	C₃₂H₅₈N₂O₇S
Chemical formula	C₃₂H₅₈N₂O₇S
Hygroscopic	Hygroscopic
Micellar weight	6150
Quality Level	MQ300

Applications

Biological Information
Purity	≥98% by NMR

Physicochemical Information
Contaminants	DNase, RNase, and Protease: none detected

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 22-36/38 Harmful if swallowed. Irritating to eyes and skin.
S Phrase	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Harmful
Storage	+15°C to +30°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
Catalog Number	GTIN
220201-10GM	07790788048754
220201-1GM	04055977200973
220201-1KG	04055977200980
220201-250GM	04055977201017
220201-25GM	04055977201000
220201-5GM	04055977201024

Documentation

CHAPS, Molecular Biology Grade - CAS 75621-03-3 - Calbiochem SDS

Title
Safety Data Sheet (SDS)

CHAPS, Molecular Biology Grade - CAS 75621-03-3 - Calbiochem Certificates of Analysis

Title	Lot Number
220201	Enter Lot Number

References

Reference overview
Chen, Y., et al. 1992. Biochemistry 31, 2415. Ofri, D., et al. 1992. J. Neurochem. 58, 628. Ransom, R.W., et al. 1992. Biochem. Pharmacol. 43, 1823. Simonds, W.F., et al. 1992. Proc. Natl. Acad. Sci. USA 77, 4623. Yannariello-Brown, J., and Weigel, P.H. 1992. Biochemistry 31, 576. Hjelmeland, L.M. 1980. Proc. Natl. Acad. Sci. USA 77, 6368. Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 4623.

Reference overview

Brochure

Title
CALBIOSORBﾙ Technical Bulletin

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	12-November-2010 RFH
Synonyms	3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
Description	Non-denaturing zwitterionic detergent that combines features of bile salts and N-alkyl sulfobetaines. Better at solubilizing proteins than the structurally related carboxylic acid anions, and is more effective at breaking protein-protein interactions than either sodium cholate or TRITON^® X-100. Capable of solubilizing the opiate receptor to a state exhibiting reversible binding to opiates. Also capable of disaggregating P 450 to its monomeric form without denaturation. Has a small micellar molecular weight (6150 Daltons) and a high critical micellar concentration (6-10 mM). Can be removed from either gels or protein solutions by dialysis. Aggregation number: 4-14.
Form	White crystalline powder
CAS number	75621-03-3
Chemical formula	C₃₂H₅₈N₂O₇S
Purity	≥98% by NMR
Contaminants	DNase, RNase, and Protease: none detected
Solubility	H₂O (1.0 M)
Storage	+15°C to +30°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
Toxicity	Harmful
Merck USA index	14, 2044
References	Chen, Y., et al. 1992. Biochemistry 31, 2415. Ofri, D., et al. 1992. J. Neurochem. 58, 628. Ransom, R.W., et al. 1992. Biochem. Pharmacol. 43, 1823. Simonds, W.F., et al. 1992. Proc. Natl. Acad. Sci. USA 77, 4623. Yannariello-Brown, J., and Weigel, P.H. 1992. Biochemistry 31, 576. Hjelmeland, L.M. 1980. Proc. Natl. Acad. Sci. USA 77, 6368. Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 4623.

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220201 MilliporeCHAPS, Molecular Biology Grade - CAS 75621-03-3 - Calbiochem

CAS 75621-03-3 is a zwitterionic detergent that combines features of bile salts and N-alkyl sulfobetaines.

Synonyms: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

Recommended Products

Overview

Key Specifications Table

Pricing & Availability

Documentation

CHAPS, Molecular Biology Grade - CAS 75621-03-3 - Calbiochem SDS

CHAPS, Molecular Biology Grade - CAS 75621-03-3 - Calbiochem Certificates of Analysis

References

Brochure

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