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01-195 CNTF, recombinant

CNTF, recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Cell Culture UniProt Number: P26441 Entrez Gene Number: NM_000614.2
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01-195
25 µg  
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      Overview

      Replacement Information
      Description
      Catalogue Number01-195
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionCNTF, recombinant
      References
      Product Information
      PresentationLyophilized from 5mM sodium acetate, pH 6.5.
      Quality LevelMQ100
      Applications
      Key Applications
      • Cell Culture
      Biological Information
      SourceRecombinant rat Ciliary Neurotrophic Factor expressed in E. coli
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also co-transcribed with the upstream ZFP91 gene. Co-transcription from the two loci results in a transcript that contains a complete coding region for the zinc finger protein but lacks a complete coding region for ciliary neurotrophic factor.
      Gene Symbol
      • CNTF
      • HCNTF
      Purification MethodSterilized through a 0.2 micron membrane filter
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P26441 # CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
      SIZE: 200 amino acids; 22931 Da
      SUBUNIT: Homodimer.
      SUBCELLULAR LOCATION: Cytoplasm.
      TISSUE SPECIFICITY: Nervous system.
      SIMILARITY: SwissProt: P26441 ## Belongs to the CNTF family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated in a biological activity assay.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size25 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      01-195 04053252331909

      Documentation

      CNTF, recombinant SDS

      Title

      Safety Data Sheet (SDS) 

      CNTF, recombinant Certificates of Analysis

      TitleLot Number
      CNTF (recombinant protein expressed in E. coli) - 2115523 2115523
      CNTF (recombinant protein expressed in E. coli) - 2138536 2138536
      CNTF (recombinant protein expressed in E. coli) 2459019
      CNTF (recombinant protein expressed in E. coli) - 1982678 1982678
      CNTF (recombinant protein expressed in E. coli) - 2219254 2219254
      CNTF (recombinant protein expressed in E. coli) - 2318069 2318069
      CNTF (recombinant protein expressed in E. coli) - 3427185 3427185
      CNTF (recombinant protein expressed in E. coli) - 3723408 3723408
      CNTF (recombinant protein expressed in E. coli) - 3940595 3940595
      CNTF (recombinant protein expressed in E. coli) - 4164918 4164918
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