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324904 Epiregulin, Mouse, Recombinant

Epiregulin, Mouse, Recombinant is expressed in E. coli with an N-terminal methionine. Inhibits epithelial tumor growth and stimulates the growth of fibroblasts and other cell types.

Epiregulin, Mouse, Recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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324904
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Overview

Replacement Information

Key Specifications Table

Purity
≥97% by SDS-PAGE

Pricing & Availability

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324904-50UG
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      		 Glass bottle 50 μg
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      Description
      OverviewRecombinant, mouse epiregulin expressed in E. coli with an N-terminal methionine. Epiregulin is shown to inhibit epithelial tumor growth, able to stimulate growth of fibroblasts and other cell types, and has been shown to be an autocrine growth factor in human epidermal keratinocytes.
      Catalogue Number324904
      Brand Family Calbiochem®
      References
      ReferencesShirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
      Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
      Das, S.K., et al. 1997. Dev. Biol. 190, 178.
      Komurasaki, T., et al. 1997. Oncogene 15, 2841.
      Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
      Toyoda, H., et al. 1995. FEBS Lett. 377, 403.
      Product Information
      FormLiquid
      FormulationLyophilized from 0.2 µm sterile-filtered PBS, BSA.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 0.3-1 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
      Purity≥97% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: <1.0 EU/µg protein
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      324904-50UG 04055977196276

      Documentation

      Epiregulin, Mouse, Recombinant SDS

      Title

      Safety Data Sheet (SDS) 

      Epiregulin, Mouse, Recombinant Certificates of Analysis

      TitleLot Number
      324904

      References

      Reference overview
      Shirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
      Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
      Das, S.K., et al. 1997. Dev. Biol. 190, 178.
      Komurasaki, T., et al. 1997. Oncogene 15, 2841.
      Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
      Toyoda, H., et al. 1995. FEBS Lett. 377, 403.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision21-Sepmtember-2011 RFH
      DescriptionRecombinant, mouse epiregulin expressed in E. coli with an N-terminal methionine. Epiregulin is shown to inhibit epithelial tumor growth, able to stimulate growth of fibroblasts and other cell types, and has been shown to be an autocrine growth factor in human epidermal keratinocytes.
      FormLiquid
      FormulationLyophilized from 0.2 µm sterile-filtered PBS, BSA.
      Purity≥97% by SDS-PAGE
      ContaminantsEndotoxin: <1.0 EU/µg protein
      Biological activityED₅₀ = 0.3-1 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
      SolubilityReconstitute to 10 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesShirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
      Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
      Das, S.K., et al. 1997. Dev. Biol. 190, 178.
      Komurasaki, T., et al. 1997. Oncogene 15, 2841.
      Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
      Toyoda, H., et al. 1995. FEBS Lett. 377, 403.