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GF446-50UG HumanKine® Thermostable bFGF,
Human Recombinant

Engineered bFGF growth factor with enchanced thermostability compared to the wild-type bFGF protein. Allows a less vigorous feeding schedule for human es/ips and neural stem cell culture.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P09038
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GF446-50UG
50 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      SourcePurity
      HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.Product is endotoxin free (<0.5 ng/μg of protein (<5 EU/μg) and greater than 95% pure by SDS-PAGE.
      Description
      Catalogue NumberGF446-50UG
      Trade Name
      • HumanKine®
      DescriptionHumanKine® Thermostable bFGF,
      Human Recombinant
      Alternate Names
      • FGF2
      • prostatropin
      • Prostatropin
      • HBGF-2
      • BFGF
      Background InformationThe HumanKine Thermostable bFGF is engineered with enchanced thermostability compared to the wild-type bFGF protein without modification of biological function.

      Fibroblast Growth Factor-basic (bFGF) is a heparin binding growth factor which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. bFGF also exerts a potent angiogenic activity in vivo. Human bFGF is a 17.2 kDa protein containing 154 amino acid residues. bFGF synergizes with the BMP antagonist noggin to sustain undifferentiated proliferation of human embryonic stem (hES) cells under feeder-free conditions.
      References
      Product Information
      PresentationLyophilized from a 0.2 μm filtered solution of 1X PBS.
      Quality LevelMQ100
      Applications
      ApplicationEngineered bFGF growth factor with enchanced thermostability compared to the wild-type bFGF protein. Allows a less vigorous feeding schedule for human es/ips and neural stem cell culture.
      Application NotesHumanKine products are Xeno-Free
      Biological Information
      PurityProduct is endotoxin free (<0.5 ng/μg of protein (<5 EU/μg) and greater than 95% pure by SDS-PAGE.
      SourceHumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by the dose-dependent stimulation of the proliferation of the 3T3 cell line. EC50 is typically ≤0.5 ng/mL.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      GF446-50UG 04053252975950

      Documentation

      HumanKine® Thermostable bFGF,
      Human Recombinant SDS

      Title

      Safety Data Sheet (SDS) 

      HumanKine® Thermostable bFGF,
      Human Recombinant Certificates of Analysis

      TitleLot Number
      HumanKine® Thermostable bFGF VP1611152
      HumanKine® Thermostable bFGF, Human Recombinant - QVP1402051 QVP1402051
      HumanKine® Thermostable bFGF, -VP1501022 VP1501022
      HumanKine® Thermostable bFGF, -VP1501039 VP1501039
      HumanKine® Thermostable bFGF, -VP1508061 VP1508061
      HumanKine® Thermostable bFGF, -VP1509031 VP1509031
      HumanKine® Thermostable bFGF, -VP1511110 VP1511110
      HumanKine® Thermostable bFGF, -VP1602101 VP1602101
      HumanKine® Thermostable bFGF, -VP1602128 VP1602128
      HumanKine® Thermostable bFGF, -VP1604188 VP1604188
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