Optiseal–M Cartridge Filters with Hydrophobic Aervent Membrane
Recommended Products
-
TM-10L-BK Millipore BIOSCOT® Anti-A,B from the clones ES-15/ES-4, Murine IgM, Blood Grouping Reagent -
MABE1946-100UL Sigma-Aldrich Anti-LOXL2 Antibody, clone GS341 -
CR99M0203 Millipore Polygard-CR Cartridge Filter 2 in. 100 µm Code M Silicone -
8210840100 Sigma-Aldrich Tetra-n-butyl orthotitanate -
370674-5UMOL Sigma-Aldrich Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem -
8009182500 Sigma-Aldrich Dimethyl phthalate -
69749-3 Sigma-Aldrich pET-24a(+) DNA - Novagen -
ZF2000174 Milli-Q ZF2000174 -
 acetylacetonate[802699_Copper(II) acetylacetonate-ALL].jpg)
802712 Sigma-Aldrich Copper(II) acetylacetonate -
150438 Supelco SeQuant® ZIC®-pHILIC Guard Kit 20 x 2.1 mm
Overview
Specifications
Ordering Information
Documentation
Related Products & Applications
Product Families
Optiseal Cartridge Filters with Hydrophobic Aervent MembraneOptiseal filters with Aervent membrane are designed for sterilizing applications, removing particles and microorganisms from gases and solvents.Learn More >> |
Aervent–50 Disposable Filters with Hydrophobic Aervent MembraneThis sterilizing-grade filter is designed for critical small scale gas line and air venting applications.Learn More >> |
Related Products By: Application Facete
| Sterility Testing |
| Fermentation Solutions |
| Dialysis and Filtration |
Related Products By: Brand Facete
| Optiseal® |
Categories
| Biopharmaceutical Manufacturing > Downstream Processing > Sterile Filtration > Sterile Gas > Aervent |
Description
Optiseal-M filters with Aervent membrane are 0.2 µm hydrophobic cartridges. They are designed for sterilizing applications, removing particles and microorganisms from gases and solvents. They are made with PTFE membrane and polypropylene components for broad application compatibility. Optiseal-M filters with Aervent membrane are designed to be used with Millidisk housings.
Each unit is 100% integrity tested during manufacturing to guarantee integrity.
Typical Applications
The sterilizing grade rating is based on ASTM liquid bacterial retention challenge. In gases this filter will remove contamination down to 0.01 µm. Optiseal-M Aervent hydrophobic cartridges will remove particles and microorganisms from gases and liquids for low flow rates.
- Sterile tank venting
- Fermentation air applications
- Bioreactor inlet and outlet filtration
- Autoclaves
- Sterile process gases
Cartridges will also sterilize alcohol streams.
| Materials of Construction | ||
| Filter | Polytetrafluoroethylene (PTFE) | |
| Supports | Polypropylene | |
| O-ring | Silicone (SI) | |
| Connections | Not Applicable | |
| Filtration Area | 0.05 m² | |
| Maximum Differential Pressure, bar (psid) | Forward: 5.5 bar (80 psid) @ 25 °C; 1.7 bar (25 psid) @ 80 °C; 0.35 bar (5 psid) @ 135 °C. Reverse: 4.1 bar (60 psid) | |
| Bacterial Retention | Samples were quantitatively retentive of a minimum Brevundimonas diminuta challenge concentration of 1 x 10⁷ CFU/cm² using ASTM® F838 methodology. | |
| Bacterial Endotoxins | Aqueous extraction contains ≤0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test | |
| Toxicity | Component materials meet the requirements of the USP Class VI Biological Test for Plastics. The cartridges also meet the requirements of the USP General (Mouse) Safety Test. | |
| Sterilization | 80 (40 forward/40 reverse) SIP cycles of 30 min @ 135 °C | |
| Integrity Test | ||
| Bubble Point | ≥1100 mbar (16 psig) nitrogen with 70/30 % IPA/water | |