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GF347 TPO,
Human Recombinant Animal Free

TPO,
Human Recombinant Animal Free MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P40225
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GF347
10µg  
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      Overview

      Replacement Information

      Key Specifications Table

      SourcePurity
      Protein is expressed in E.coli.
      The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.      		Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
      Description
      Catalogue NumberGF347
      DescriptionTPO,
      Human Recombinant Animal Free
      Alternate Names
      • Thrombopoeitin
      • THPO
      Background InformationTPO, or thrombopoietin, is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity.
      Recombinant human TPO is a fully biologically active 174 amino acid polypeptide (18.6 kDa), which contains the erythropoietin-like domain of the full length TPO protein.
      References
      Product Information
      PresentationProduct is presented in 0.1% TFA and is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ100
      Applications
      Biological Information
      PurityProduct endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
      SourceProtein is expressed in E.coli.
      The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceDetermined by its ability to stimulate the proliferation of human MO7e cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
      Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
      Packaging Information
      Material Size10µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      GF347 04053252979064

      Documentation

      TPO,
      Human Recombinant Animal Free SDS

      Title

      Safety Data Sheet (SDS) 

      TPO,
      Human Recombinant Animal Free Certificates of Analysis

      TitleLot Number
      TPO, Human Recombinant Animal Free - Q2447027 Q2447027
      TPO, Human Recombinant Animal Free - 3213874 3213874
      TPO, Human Recombinant Animal Free - 3231895 3231895
      TPO, Human Recombinant Animal Free - 3389898 3389898
      TPO, Human Recombinant Animal Free - 3860518 3860518
      TPO, Human Recombinant Animal Free - 3923529 3923529
      TPO, Human Recombinant Animal Free - 4058967 4058967
      TPO, Human Recombinant Animal Free - 4138820 4138820
      TPO, Human Recombinant Animal Free - 4161007 4161007
      TPO, Human Recombinant Animal Free Recombinant Protein 3118124

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