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584222 Tetrahydrouridine - CAS 18771-50-1 - Calbiochem

Potent competitive inhibitor of cytidine deaminase. Also available as a 100 mM solution in H2O.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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584222
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
18771-50-1C₉H₁₆N₂O₆

Pricing & Availability

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584222-10MG
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      		 Plastic ampoule 10 mg
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      Description
      OverviewPotent competitive inhibitor of cytidine deaminase. Also available as a 100 mM solution in H2O(Cat. No. 584223).
      Catalogue Number584222
      Brand Family Calbiochem®
      References
      ReferencesYusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
      Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
      Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
      Riva, C., et al. 1992. Chemotherapy 38, 358.
      Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
      Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.
      Product Information
      CAS number18771-50-1
      FormWhite to off-white solid
      Hill FormulaC₉H₁₆N₂O₆
      Chemical formulaC₉H₁₆N₂O₆
      Hygroscopic Hygroscopic
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥90% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSUW5798980
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Aqueous stock solutions (at neutral or basic pH) are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      584222-10MG 04055977264944

      Documentation

      Tetrahydrouridine - CAS 18771-50-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Tetrahydrouridine - CAS 18771-50-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      584222

      References

      Reference overview
      Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
      Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
      Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
      Riva, C., et al. 1992. Chemotherapy 38, 358.
      Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
      Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision21-June-2013 JSW
      DescriptionA potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies.
      FormWhite to off-white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number18771-50-1
      RTECSUW5798980
      Chemical formulaC₉H₁₆N₂O₆
      Purity≥90% by TLC
      SolubilityH₂O (200 mg/ml)
      Storage Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Aqueous stock solutions (at neutral or basic pH) are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesYusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
      Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
      Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
      Riva, C., et al. 1992. Chemotherapy 38, 358.
      Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
      Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.