506153 Sigma-Aldrichp38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem
The p38 MAP Kinase Inhibitor IV, also referenced under CAS 1638-41-1, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
More>> The p38 MAP Kinase Inhibitor IV, also referenced under CAS 1638-41-1, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 2,2ʹ-Sulfonyl-bis-(3,4,6-trichlorophenol), MT4
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Overview
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Key Specifications Table
| CAS # | Empirical Formula |
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| 1638-41-1 | C₁₂H₄Cl₆O₄S |
Pricing & Availability
| Catalog Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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| 506153-10MG |
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Plastic ampoule | 10 mg |
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| Description | |
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| Overview | A cell-permeable symmetrical sulfone compound that acts as a potent and ATP-competitive inhibitor of p38α/β MAPK (IC50 = 130 and 550 nM, respectively), while exihibiting much reduced activity (≤23% inhibition at 1 µM) against p38γ/δ, ERK1/2, and JNK1/2/3. Shown to be more effective than SB 203850 (Cat. Nos. 559389, 559395, and 559398) in inhibiting LPS-induced IL-1β release from hPBMC (100% vs. 50% inhibition with 100 µM respective inhibitor). |
| Catalogue Number | 506153 |
| Brand Family | Calbiochem® |
| Synonyms | 2,2ʹ-Sulfonyl-bis-(3,4,6-trichlorophenol), MT4 |
| References | |
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| References | Liu, Y.C., et al. 2007. Biochem. Biophys. Res. Commun. 352, 656. |
| Product Information | |
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| CAS number | 1638-41-1 |
| Form | Light yellow solid |
| Hill Formula | C₁₂H₄Cl₆O₄S |
| Chemical formula | C₁₂H₄Cl₆O₄S |
| Hygroscopic | Hygroscopic |
| Structure formula Image | |
| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥95% by HPLC |
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| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Catalog Number | GTIN |
| 506153-10MG | 04055977272239 |
Documentation
p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem SDS
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p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 506153 |
References
| Reference overview |
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| Liu, Y.C., et al. 2007. Biochem. Biophys. Res. Commun. 352, 656. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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