February 23-25, 2016 - San Francisco, CA
Event Details
Join us for our Annual Chromatography User Group Meeting and meet with other chromatography peers to share best practices, exchange common industry observations, and identify existing challenges and future trends as well as needs in affinity and ion exchange chromatography.
Who should attend?Biotechnology and biopharmaceutical industry professionals, including those in chromatography R&D, process development, production management and process engineering.
Building on the success of previous meetings, this user forum is now in
its 12th year. Chaired by Tim Breece, Senior Scientist in Purification Development, XOMA Corporation, USA, we will discuss a variety of topics that include:
- Process development: resin selection and optimization case studies
- High throughput screening: case studies, challenges and needs
- Robust impurity removal throughout downstream process
- Protein A intermediate wash and elution optimization
- IEX process characterization including the use of DOE tools
- Selectivity in IEX systems: models and tools to characterize separations (e.g. mAb monomer and aggregates)
- Scale-up and scale-down of Protein A and IEX processes
- Cleaning and sanitization of Protein A and IEX resins
- Regulatory considerations for Protein A and IEX
- Removal and characterization of aggregates
- Process productivity and cost analysis case studies
- Virus clearance case studies on Protein A and IEX
- Continuous chromatography and flow through downstream processing for mAbs
- Best practices for column packing and handling at all scales
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