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1.15640

Sigma-Aldrich

Aldehyde dehydrogenase

lyophilized, from yeast, pkg of 100 units/vial

Synonym(s):

Aldehyde dehydrogenase

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352204
EC Index Number:
232-846-3
NACRES:
NA.21
Pricing and availability is not currently available.

biological source

yeast

Quality Level

form

lyophilized

specific activity

≥15 U/mg (calculated on the protein content)

packaging

pkg of 100 units/vial

storage temp.

2-8°C

General description

Aldehyde dehydrogenases (ALDH) form a superfamily of phase-I oxidases and are evolutionarily conserved in eubacteria, eukaryotes, archaea, and other living organisms. ALDH is abundantly expressed in the liver and found in hepatic tissue. They are localized to the cytoplasm, mitochondria, endoplasmic reticulum, and nucleus.[1]

Biochem/physiol Actions

Aldehyde dehydrogenases (ALDH) metabolize endogenous and exogenous reactive compounds to maintain cellular homeostasis. This group of enzymes catalyzes the NADP+-dependent irreversible oxidation of aldehydes to form carboxylic acids. ALDH isozymes have broad substrate specificity.[1] Inactivation of ALDH causes cytotoxicity due to substrate accumulation.[2]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Questions

  1. Bonjour, combien de mg y-a-t-il dans ce vial ?

    1 answer
    1. The amount of product per vial can be determined using the specific activity reported in the lot specific Certificate of Analysis. For example, product 1156400001, lot K53163040, has an activity value of 118 units/vial and a specific activity value of 31 units/mg which would give 3.80 mg/vial.

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