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MABN782 Anti-Amyloid-like protein 2, clone 5C9.3

MABN782
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN782
      DescriptionAnti-Amyloid-like protein 2, clone 5C9.3
      Alternate Names
      • APLP-2
      • APLP2
      • APPH
      • Amyloid protein homolog
      • CDEI box-binding protein
      • CDEBP
      • Amyloid-like protein 2
      Background InformationAmyloid precursor-like protein 2 is encoded by the APLP2 (or APPL2) gene in human and a member of the Amyloid precursor protein (APP) family with APP & APPL1 being the other two members. It contains heparin-, copper- and zinc- binding domains at the N-terminal portion, BPTI/Kunitz inhibitor and E2 domains in the middle, and transmembrane and intracellular domains at the C-terminal region. APLP2 & APP are essential modulators of glucose & insulin homeostasis, as well as of neuromuscular transmission, spatial learning & synaptic plasticity. APLP2 is known to interact with major histocompatibility complex (MHC) class I molecules and hFe65L.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-Amyloid-like protein 2 Antibody, clone 5C9.3 is an antibody against Amyloid-like protein 2 for use in Western Blotting and Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Amyloid-like protein 2 in human kidney and human cerebral cortex tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Amyloid-like protein 2.
      Clone5C9.3
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • APLP2
      • APPL2
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~87 kDa observed. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in SH-SY5Y cell lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected Amyloid-like protein 2 in 10 µg of SH-SY5Y cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      MABN782 04055977136838