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MABD45 Anti-DDPIV/CD26 Antibody, clone 9F1.2

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MABD45
100 μg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABD45
      DescriptionAnti-DDPIV/CD26 Antibody, clone 9F1.2
      Alternate Names
      • Dipeptidyl peptidase 4
      • ADABP
      • Adenosine deaminase complexing protein 2
      • ADCP-2
      • Dipeptidyl peptidase IV
      • DPP IV
      • T-cell activation antigen CD26
      • TP103
      • CD26
      • Dipeptidyl peptidase 4 membrane form
      • Dipeptidyl peptidase IV membrane form
      • Dipeptidyl peptidase 4 soluble form
      • Dipeptidyl peptidase IV soluble form
      • DDPIV/CD26
      Background InformationDipeptidyl peptidase 4 (EC 3.4.14.5; UniProt P27487; also known as ADABP, ADCP-2, Adenosine deaminase complexing protein 2, DPP IV, T-cell activation antigen CD26, Adenosine deaminase complexing protein 2, Dipeptidyl peptidase 4, Dipeptidylpeptidase IV, TP103) is encoded by the DPP4 (also known as CD26, ADCP2) gene (Gene ID 1803) in human. DPPIV is a homodimeric serine exopeptidase that cleaves x-proline dipeptides from the N-terminus of polypeptides. It is involved in many cellular processes such as activation of cytokines, differentiation, and cell-matrix interactions. Inhibition of DPPIV has been reported to be an effective treatment for type II diabetes. Also, DPPIV acts as a functional receptor for the newly discovered Middle East respiratory syndrome (MERS) coronavirus.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG2aκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-DDPIV/CD26 Antibody, clone 9F1.2 is validated for use in Western Blotting for the detection of DDPIV/CD26.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to the extracellular domain of human DDPIV/CD26.
      Epitopeextracellular domain
      Clone9F1.2
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityReacts with both membrane-bound (MDPP) and soluble (SDPP) forms.
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • DPP4
      • ADCP2
      • CD26
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~100 kDa observed. Due to glycosylation, target band appears larger than the calculated molecular weight of 88.3 (MDPP) & 84.4 (SDPP) kDa. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in PC3 cell lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected DDPIV/CD26 in 10 µg of PC3 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      MABD45 04055977182576

      Documentation

      Anti-DDPIV/CD26 Antibody, clone 9F1.2 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-DDPIV/CD26 Antibody, clone 9F1.2 Certificates of Analysis

      TitleLot Number
      Anti-DDPIV/CD26, clone 9F1.2 - 3763307 3763307
      Anti-DDPIV/CD26, clone 9F1.2 - 4158372 4158372
      Anti-DDPIV/CD26, clone 9F1.2 -Q2589912 Q2589912

      Technical Info

      Title
      Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
      White Paper: Further considerations of antibody validation and usage.