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ABS111 Anti-Fidgetin Antibody

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ABS111
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS111
      DescriptionAnti-Fidgetin Antibody
      Background InformationFidgetin is a AAA protein that belongs to the meitoic or subfamily-7 (SF7) group of ATPases. These enzymes are associated with many different general cellular activities, such as but not limited to, membrane fusion, proteolysis, metabolic signaling, peroxisome biogenesis, endosome sorting, and meiotic spindle formation. However, the specific functions and mechanisms for SF7 AAA proteins remain largely unclear. It is reported that mutant Fidgetin is found in a mammalian developmental mutant and is suggested to play in role in embryonic development.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Mouse brain tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Fidgetin Antibody is an antibody against Fidgetin for use in WB.
      Key Applications
      • Western Blotting
      Application NotesWestern Blot Analysis: 1 µg/mL from a representative lot detected Figetin in U20S cell lysate.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Fidgetin.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Mouse
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • FIGN
      Purification MethodAffinity Purfied
      UniProt Number
      UniProt SummarySUBCELLULAR STRUCTURE: Interacts with AKAP8 (via C-terminus).

      SUBCELLULAR LOCATION: Nucleus matrix.
      Molecular Weight~60 kDa observed.
      The calculated molecular weight of this protein is 82 kDa, but is observed at ~60 kDa due to a splice variant (Yang, Y., et al. (2005). Experimental Cell Research. 304:50-58).
      Uncharacterized bands may be observed at ~25 kDa and ~57 kDa in some tissue lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in mouse brain tissue lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected Figetin in 10 µg of mouse brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      ABS111 04053252755095