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ABF221 Anti-IRAK-2 Antibody

Anti-IRAK-2 Antibody is a highly specific rabbit polyclonal antibody, that targets IRAK2 & has been tested in western blotting, ICC & Immunofluorescence.

Anti-IRAK-2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunological Signaling Gene Symbol: IRAK2 UniProt Number: O43187
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ABF221
100 µg  
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      Overview

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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICC, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABF221
      DescriptionAnti-IRAK-2 Antibody
      Alternate Names
      • Interleukin-1 receptor-associated kinase-like 2
      • IRAK-2
      Background InformationInterleukin-1 receptor-associated kinase-like 2 (IRAK-2) binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. IRAK-2 also mediates activation of NF-κB, which is a pivotal transcription factor mediating inflammatory and immune response. Additionally, IRAK-2 may play an important role in IL-1R and TLR mediated inflammatory response. IRAK-2 is expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
      References
      Product Information
      FormatAffinity Purified
      Control
      • HeLa and K562 cell lysates
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-IRAK-2 Antibody is a highly specific rabbit polyclonal antibody, that targets IRAK2 & has been tested in western blotting, ICC & Immunofluorescence.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunofluorescence
      Application NotesImmunocytochemistry Analysis: 2 µg/mL from a representative lot detected IRAK-2 in HeLa cells.

      Immunofluorescence Analysis: 10 µg/mL from a representative lot detected IRAK-2 in HeLa cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human IRAK-2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • IRAK2
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~65 kDa observed. Uncharacterized bands may appear in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in HeLa and K562 cell lysates.

      Western Blot Analysis: 2 µg/mL of this antibody detected IRAK-2 in 15 µg of HeLa and K562 cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      ABF221 04053252910128