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ABS1017 Anti-PHLPP2 Antibody

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ABS1017
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS1017
      DescriptionAnti-PHLPP2 Antibody
      Alternate Names
      • PHLPP2
      • PH domain leucine-rich repeat-containing protein phosphatase 2
      • PH domain leucine-rich repeat-containing protein phosphatase-like
      • PHLPP-like
      Background InformationPH Domain And Leucine Rich Repeat Protein Phosphatase 2 is encoded by the PHLPP2 gene. It is known to catalyze the dephosphorylation of pSer473 of AKT1 and pSer660 of PRKCbeta-II, as well as pSer657 of PRKCalpha.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-PHLPP2 Antibody is an antibody against PHLPP2 for use in Western Blotting and Immunocytochemistry.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: 2.0 ug/mL from a representative lot detected PHLPP2 in HUVEC cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding within the PP2C-like domain of human PHLPP2.
      EpitopeWithin PP2C-like Domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Species Reactivity NoteHuman. Predicted to react with Bovine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PHLPP2
      • KIAA0931
      • PHLPPL
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~150 kDa observed. Predicted to cross-react to all isoforms. Isoform 2 (~107kDa) can possibly be detected at longer exposures/higher concentrations or in certain tissues.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HUVEC cell lysate.

      Western Blotting Analysis: 0.2 µg/mL of this antibody detected PHLPP2 in 10 µg of HUVEC cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      ABS1017 04055977136364