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MABD633-25UG Anti-SALL2 Antibody, clone 2B9.1

Anti-SALL2, clone 2B9.1, Cat. No. MABD633, is a highly specific mouse monoclonal antibody that targets Sal-like protein 2 and has been tested for use in Immunohistochemistry (Paraffin) and Western Blotting.

Anti-SALL2 Antibody, clone 2B9.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Gene Symbol: SALL2, KIAA0360, SAL2, ZNF795 UniProt Number: Q9Y467
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MABD633-25UG
25 μg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABD633-25UG
      DescriptionAnti-SALL2 Antibody, clone 2B9.1
      Alternate Names
      • Sal-like protein 2
      • Zinc finger protein 795
      • Zinc finger protein SALL2
      • Zinc finger protein Spalt-2
      • Sal-2
      • hSal2
      Background InformationSal-like protein 2 (UniProt: Q9Y467; also known as Zinc finger protein 795, Zinc finger protein SALL2, Zinc finger protein Spalt-2, Sal-2, hSal2) is encoded by the SALL2 (also known as KIAA0360, SAL2, ZNF795) gene (Gene ID: 6297) in human. SALL2 is a member of the Sal C2H2-type zinc-finger protein family that serves as a transcription factor and plays a role in eye development before, during, and after optic fissure closure. Two isoforms of SALL2 have been described (105 kDa and 21 kDa) that are produced by alternative splicing. SALL2 contains seven C2H2-type zinc-finger regions. Its highest expression is observed in different areas of adult brain and lower levels are detected in heart muscle. It is expressed throughout the retina and lens vesicle as well as the periocular mesenchyme. In fetal brain it is exclusively found in pontine nuclei and is expressed at five weeks of development, the stage at which optic fissure closure begins. Mutations in SALL2 gene are known to cause Coloboma, ocular, autosomal recessive syndrome that results in abnormal morphogenesis of the optic cup and stalk, and incomplete fusion of the fetal intra-ocular fissure during gestation.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-SALL2, clone 2B9.1, Cat. No. MABD633, is a highly specific mouse monoclonal antibody that targets Sal-like protein 2 and has been tested for use in Immunohistochemistry (Paraffin) and Western Blotting.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SALL2 in human cerebellum tissues.
      Biological Information
      ImmunogenGST/His-tagged recombinant fragment corresponding to 90 amino acids from the C-terminal region of human Sal-Like protein 2.
      Clone2B9.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityClone 2B9.1 detects Sal-like protein 2 in human cells. It targets an epitope within 90 amino acids from the C-terminal region.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Species Reactivity NoteHuman.
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SALL2
      • KIAA0360
      • SAL2
      • ZNF795
      Purification MethodProtein G purified
      UniProt Number
      Molecular Weight~130 kDa observed; 105.31 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in H9 human embryonic stem cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected SALL2 in H9 human embryonic stem cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size25 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      MABD633-25UG 04054839441219