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AB9094-I Anti-Sodium Pump Subunit alpha-2 Antibody

Detect Sodium Pump Subunit alpha-2 using this Anti-Sodium Pump Subunit alpha-2 Antibody validated for use in Western Blotting, Immunohistochemistry (Paraffin) and Immunoprecipitation.

Anti-Sodium Pump Subunit alpha-2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: Atp1a2 UniProt Number: P06686
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AB9094-I
100 µL  
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      Overview

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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IH(P), IPRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9094-I
      ReplacesAB9094
      DescriptionAnti-Sodium Pump Subunit alpha-2 Antibody
      Alternate Names
      • Sodium/potassium-transporting ATPase subunit alpha-2
      • Na(+)/K(+) ATPase alpha-2 subunit
      • Na(+)/K(+) ATPase alpha(+) subunit
      • Sodium pump subunit alpha-2
      • Sodium Pump Subunit alpha-2
      • Anti-Sodium Pump (Na+ pump (Na+-K+-ATPase)) α 2 Isoform
      • Sodium/potassium-transporting ATPase subunit alpha-2
      • ATP1A2
      Background InformationSodium/potassium-transporting ATPase subunit alpha-2 (EC 3.6.3.9; UniProt P06686; also known as Na+/K+ -ATPase alpha 2 subunit, Na(+)/K(+) ATPase alpha(+) subunit, Sodium pump subunit alpha-2) is encoded by the Atp1a2 (also known as RATATPA2) gene (Gene ID 24212) in rat. Mammalian Na+/K+ ATPase is a heteromultimeric complex composed of alpha, beta, and gamma subunits. The alpha subunit catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ across the plasma membrane. The alpha subunit contains ten transmembrane domains with both its N- and C-termini in the cytoplasm. More than 50 mutations have been identified affecting the human ATP1A2 and ATP1A3 genes that are known to cause rapid-onset Dystonia Parkinsonism, familial hemiplegic migraine, alternating hemiplegia of childhood, and variants of familial hemiplegic migraine with neurological complications including seizures and various mood disorders.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Sodium Pump Subunit alpha-2 using this Anti-Sodium Pump Subunit alpha-2 Antibody validated for use in Western Blotting, Immunohistochemistry (Paraffin) and Immunoprecipitation.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      • Immunoprecipitation
      Application NotesImmunohistochemistry Analysis (IHC): A representative lot detected Sodium Pump Subunit alpha-2 in human (1:1,000) and rat (1:250) cerebellum tissue sections.

      Immunoprecipitation Analysis (IP): 10 ug from a representative lot immunoprecipitated Sodium Pump Subunit alpha-2 in 500 µg of rat brain tissue lysate.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the second cytoplasmic domain of rat Sodium Pump Subunit alpha-2.
      EpitopeSecond cytoplasmic domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityReacts with Sodium Pump (Na+ pump (Na+-K+-ATPase)) alpha 2 isoform. The antibody does not cross react with other Na+-K+-ATPase alpha isoforms.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteHuman, Mouse, Rat. Predicted to react with Bovine, Porcine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Atp1a2
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~100 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat brain tissue lysate.

      Western Blotting Analysis: A 1:4,000 dilution of this antibody detected Sodium Pump Subunit alpha-2 in 10 µg of rat brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      AB9094-I 04055977173390

      Documentation

      Anti-Sodium Pump Subunit alpha-2 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Sodium Pump Subunit alpha-2 Antibody Certificates of Analysis

      TitleLot Number
      Anti-Sodium Pump Subunit alpha-2 - 3228351 3228351
      Anti-Sodium Pump Subunit alpha-2 - 3280268 3280268
      Anti-Sodium Pump Subunit alpha-2 - 3448549 3448549
      Anti-Sodium Pump Subunit alpha-2 - 3700881 3700881
      Anti-Sodium Pump Subunit alpha-2 - 3907844 3907844
      Anti-Sodium Pump Subunit alpha-2 - 4166974 4166974
      Anti-Sodium Pump Subunit alpha-2 -2796794 2796794
      Anti-Sodium Pump Subunit alpha-2 -2855648 2855648
      Anti-Sodium Pump Subunit alpha-2 -Q2574768 Q2574768
      Anti-Sodium Pump Subunit alpha-2 Polyclonal Antibody 3009967
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      Technical Info

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      White Paper: Further considerations of antibody validation and usage.