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07-677-I Anti-acetyl-Histone H3 (Lys56) Antibody

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07-677-I
200 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, DB, ChIPRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue Number07-677-I
      Replaces07-677
      DescriptionAnti-acetyl-Histone H3 (Lys56) Antibody
      Alternate Names
      • Histone H3.1
      • Histone H3/a
      • Histone H3/b
      • Histone H3/c
      • Histone H3/d
      • Histone H3/f
      • Histone H3/h
      • Histone H3/i
      • Histone H3/j
      • Histone H3/k
      • Histone H3/l
      • H3K56Ac
      • Histone H3 (acetyl K56)
      • Histone H3 K56ac
      Background InformationHistone H3 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H3 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).
      References
      Product Information
      FormatAffinity Purified
      Control
      • HeLa acid extract, sodium butyrate treated HeLa acid extract, colcemid treated HeLa acid extract, recombinant Histone H3, recombinant Histone H4, and recombinant Histone H2A
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-acetyl-Histone H3 (Lys56) is an antibody targeting the acetyl-Histone H3 (Lys56) protein, validated for use in WB & ChIP.
      Key Applications
      • Western Blotting
      • Dot Blot
      • Chromatin Immunoprecipitation (ChIP)
      Application NotesDot Blot (Specificity) Analysis: A representative lot detected acetyl-Histone H3 (Lys56) in an Absurance™ Histone H3 Antibody Specificity Array (Cat. No. 16-667).

      Chromatin Immunoprecipitation Analysis: A representative lot immunoprecipitated acetyl-Histone H3 (Lys56) from HeLa cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Histone H3 acetylated at Lys56.
      EpitopeAcetylated Lys56
      HostRabbit
      SpecificityThis antibody recognizes Histone H3 acetylated at Lys56.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • HIST1H3A
      • H3FA
      • HIST1H3B
      • H3FL
      • HIST1H3C
      • H3FC
      • HIST1H3D
      • H3FB
      • HIST1H3E
      • H3FD
      • HIST1H3F
      • H3FI
      • HIST1H3G
      • H3FH
      • HIST1H3H
      • H3FK
      • HIST1H3I
      • H3FF
      • HIST1H3J
      • H3FJ
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~17 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in HeLa acid extract, sodium butyrate treated HeLa acid extract, colcemid treated HeLa acid extract, recombinant Histone H3, recombinant Histone H4, and recombinant Histone H2A.

      Western Blot Analysis: A 1:405 dilution of this antibody detected acetyl-Histone H3 (Lys56) in sodium butyrate treated HeLa acid extract.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      07-677-I 04053252828751

      Documentation

      Anti-acetyl-Histone H3 (Lys56) Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-acetyl-Histone H3 (Lys56) Antibody Certificates of Analysis

      TitleLot Number
      Anti-acetyl-Histone H3 (Lys56) 2471008
      Anti-acetyl-Histone H3 (Lys56) - 2379499 2379499
      Anti-acetyl-Histone H3 (Lys56) - Q2112544 Q2112544
      Anti-acetyl-Histone H3 (Lys56) - 2227207 2227207
      Anti-acetyl-Histone H3 (Lys56) - 3270769 3270769
      Anti-acetyl-Histone H3 (Lys56) - 3744328 3744328
      Anti-acetyl-Histone H3 (Lys56) - 4180354 4180354
      Anti-acetyl-Histone H3 (Lys56) -2514206 2514206
      Anti-acetyl-Histone H3 (Lys56) -2574090 2574090
      Anti-acetyl-Histone H3 (Lys56) -2601732 2601732

      Technical Info

      Title
      White Paper - The Message in the Marks: Deciphering Cancer Epigenetics

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies