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SCT082 BioTracker Red MAO-A Live Cell Dye

Specific two-photon fluorogenic probe for detecting and visualizing MAO-A activity in live cells, mouse and human tissues.

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SCT082
1 mg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberSCT082
      DescriptionBioTracker Red MAO-A Live Cell Dye
      OverviewMonoamine oxidases (MAOs) are important enzymes that catalyze the transformation of various neurotransmitters including serotonin, dopamine, and phenethylamine. They have two functionally distinct but structurally similar isoforms (MAO-A and MAO-B). The ability to differentiate the isoforms by using fluorescence detection/imaging technology is biologically relevant, but challenging with currently available chemical tools (1).

      BioTracker Red MAO-A Live Cell Dye is a specific two-photon fluorogenic probe for detecting and visualizing MAO-A activity. This probe may be used to detect MAO-A enzymatic activities in various biological samples, including live mammalian cells, mouse and human tissues by using two-photon fluorescence microscopy with minimal cytotoxicity (1).

      Reference:
      1. Fang, H., Zhang, H., Li, L., Ni, Y., Shi, R., Li, Z., ... & Huang, W. (2020). Rational Design of a Two‐Photon Fluorogenic Probe for Visualizing Monoamine Oxidase A Activity in Human Glioma Tissues. Angewandte Chemie, 132(19), 7606-7611.
      Alternate Names
      • Live Cell Imaging Probe
      References
      Product Information
      Detection methodFluorescence
      PresentationLyophilized. Yellow solid.
      Applications
      ApplicationSpecific two-photon fluorogenic probe for detecting and visualizing MAO-A activity in live cells, mouse and human tissues.
      Key Applications
      • Cell Based Assays
      Application NotesLive cell fluorescent imaging
      Biological Information
      Molecular Weight266.38
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssurancePurity ≥ 98% confirmed by HPLC. Identification confirmed by HNMR, LC-MS, and elemental analysis.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C, desiccate and protect from light
      Note: Centrifuge vial briefly to collect contents at bottom of vial before opening
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      SCT082 04061841827955