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SCC209 Caco-2/TC-7 Human Colon Adenocarcinoma Cell Line

Caco-2/TC-7 human colon adenocarcinoma cell line is a useful model for intestinal drug permeability and absorption studies.

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SCC209
≥1X10⁶ cells/vial   
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      Overview

      Replacement Information
      Description
      Catalogue NumberSCC209
      DescriptionCaco-2/TC-7 Human Colon Adenocarcinoma Cell Line
      Alternate Names
      • Caco-2/TC7
      • Caco2/TC7
      • TC-7
      • TC7
      Background InformationCaco-2/TC-7 Human Colon Adenocarcinoma Cell Line was isolated from a late passage of the parental Caco-2 cell line and comprises a more homogeneus population of cells that exhibit the characteristic functions of small intestinal enterocytes including organization of the apical brush border, distribution of the associated hydrolase sucrase-isomaltase (SI), more developed intercellular tight junctions and a shorter differentiation time (1).

      Reference:
      1. J. Cell Sci. 1994; 107(Pt 1): 213-225
      References
      Product Information
      Applications
      ApplicationCaco-2/TC-7 human colon adenocarcinoma cell line is a useful model for intestinal drug permeability and absorption studies.
      Key Applications
      • Cell Culture
      • Drug Transport
      Application NotesThis product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact licensing@emdmillipore.com.
      Biological Information
      Cell Line Type
      • Cancer Cells
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assurance• Each vial contains ≥ 1X10⁶ viable cells.
      • Cells are tested negative for infectious diseases by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.
      • Cells are verified to be of human origin and negative for inter-species contamination from rat, mouse, chinese hamster, Golden Syrian hamster, and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.
      • Cells are negative for mycoplasma contamination.
      • Each lot of cells is genotyped by STR analysis to verify the unique identity of the cell line.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
      Packaging Information
      Material Size≥1X10⁶ cells/vial
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      SCC209 04061841828006