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208698 Calmodulin, Human Brain

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208698
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Overview

Replacement Information

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208698-500UG
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      Plastic ampoule 500 μg
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      Description
      OverviewCalmodulin purifed from human brain.
      Catalogue Number208698
      Brand Family Calbiochem®
      SynonymsCaM, Ca2+/Calmodulin
      References
      ReferencesO'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
      Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
      Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
      Product Information
      Unit of DefinitionOne unit is defined as the amount of calmodulin that will give rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
      FormLyophilized
      FormulationLyophilized from protein solution with 2 mM EDTA.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by Native PAGE
      SourcePrepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Aqueous stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      208698-500UG 04055977203356

      Documentation

      Calmodulin, Human Brain SDS

      Title

      Safety Data Sheet (SDS) 

      Calmodulin, Human Brain Certificates of Analysis

      TitleLot Number
      208698

      References

      Reference overview
      O'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
      Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
      Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-May-2008 RFH
      SynonymsCaM, Ca2+/Calmodulin
      DescriptionCalmodulin purifed from human brain. Calmodulin is a ubiquitous Ca2+-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca2+-calmodulin complex is involved in the maintenance of intracellular Ca2+ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate.
      FormLyophilized
      FormulationLyophilized from protein solution with 2 mM EDTA.
      SourcePrepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Purity≥95% by Native PAGE
      Unit definitionOne unit is defined as the amount of calmodulin that will give rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
      SolubilityReconstitute with distilled water. H₂O (1 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Aqueous stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
      Toxicity Standard Handling
      ReferencesO'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
      Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
      Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.