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EI6 Chymostatin

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EI6
100 mg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberEI6
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionChymostatin
      OverviewChymostatin. M.W. 604.92

      Mixture of types A, B and C. Inhibits Chymotrypsin-like serine proteases including alpha, beta, gamma and delta chymotrtrypsins.

      Sequence:

      [(S)-1-Carboxy-2-Phenylethyl]-Carbamoyl-a-[2-Iminohexahydro-4(S)-Pyrimidyl]-(S)-Glycyl-X-Phenylalaninal

      X: L-Leu (type A), L-Ile (type B), L-Val (type C)

      Working concentrations 10-100μM.

      Stable for several hours. Soluble in DMSO and glacial acetic acid. Solutions are stable for a month at -20ºC.

      5mg/825 microliters in DMSO = 10mM solution.

      Dilute 1:100 for 100μM working solution.
      References
      Product Information
      PresentationLyophilized. Dissolve in dimethylsulfoxide (DMSO). After powder is thoroughly dissolved, dilute the DMSO solution with 0.9% NaCl. The concentration of DMSO should be maintained at 10% or higher. Otherwise chymostatin may precipitate from the solution.



      Example: Reconstitute 1 mg of chymostatin with 1.65 mL of DMSO. Then add 14.85 mL of 0.9% NaCl. This furnishes a 10-4 M solution. No preservatives added.
      Quality LevelMQ100
      Applications
      Key Applications
      • Inhibits Activity/Function
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain lyophilized material at -20ºC for up to one year. Store reconstituted product in aliquots at -20ºC for up to 3-4 weeks. Do not thaw and refreeze.
      Packaging Information
      Material Size100 mg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      EI6 04053252619915

      Documentation

      Chymostatin SDS

      Title

      Safety Data Sheet (SDS) 

      Chymostatin Certificates of Analysis

      TitleLot Number
      CHYMOSTATIN (Synthetic) - 2385924 2385924
      CHYMOSTATIN (Microbial Streptomyces) 2984212
      CHYMOSTATIN (Microbial Streptomyces) 2984212A
      CHYMOSTATIN (Microbial Streptomyces) 3120600
      CHYMOSTATIN (Microbial Streptomyces) - 3199241 3199241
      CHYMOSTATIN (Microbial Streptomyces) - 3229401 3229401
      CHYMOSTATIN (Microbial Streptomyces) - 3275582 3275582
      CHYMOSTATIN (Microbial Streptomyces) - 3316050 3316050
      CHYMOSTATIN (Microbial Streptomyces) - 3386496 3386496
      CHYMOSTATIN (Microbial Streptomyces) - 3389370 3389370

      References

      Reference overviewPub Med ID
      Chymostatin, a new chymotrypsin inhibitor produced by actinomycetes.
      Umezawa, H, et al.
      J. Antibiot., 23: 425-7 (1970)  1970

      5453321 5453321

      Technical Info

      Title
      Protein Blotting Handbook: 6th Edition