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235135 Corticosterone - CAS 50-22-6 - Calbiochem

Corticosteroid hormone synthesized in response to stress.

Corticosterone - CAS 50-22-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (11β)-11,21-Dihydroxypregn-4-ene-3,20-dione, Reichstein’s substance H

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235135
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
50-22-6C₂₁H₃₀O₄

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      Description
      OverviewCorticosteroid hormone synthesized in response to stress. Binds to and activates mineralocorticoid and glucocorticoid receptors, resulting in altered expression which eventually affects ionic conductances through the membrane. Also induces apoptosis in murine bone marrow.
      Catalogue Number235135
      Brand Family Calbiochem®
      Synonyms(11β)-11,21-Dihydroxypregn-4-ene-3,20-dione, Reichstein’s substance H
      References
      ReferencesGarvy, B.A., et al. 1993. Immunology 80, 587.
      DeKloet, E.R. 1992. Ann. N.Y. Acad. Sci. 663, 357.
      Joels, M., and deKloet, E.R. 1992. Trends Neurosci. 15, 25.
      Product Information
      CAS number50-22-6
      ATP CompetitiveN
      FormOff-white crystalline powder
      Hill FormulaC₂₁H₃₀O₄
      Chemical formulaC₂₁H₃₀O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMineralocorticoid and glucocorticoid receptors
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSGM7650000
      Safety Information
      R PhraseR: 62-63

      Possible risk of impaired fertility.
      Possible risk of harm to the unborn child.
      S PhraseS: 22-36

      Do not breathe dust.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      235135-1GM 04055977199642

      Documentation

      Corticosterone - CAS 50-22-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Corticosterone - CAS 50-22-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      235135

      References

      Reference overview
      Garvy, B.A., et al. 1993. Immunology 80, 587.
      DeKloet, E.R. 1992. Ann. N.Y. Acad. Sci. 663, 357.
      Joels, M., and deKloet, E.R. 1992. Trends Neurosci. 15, 25.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision01-May-2019 JSW
      Synonyms(11β)-11,21-Dihydroxypregn-4-ene-3,20-dione, Reichstein’s substance H
      DescriptionCorticosteroid hormone synthesized in response to stress. Binds to and activates mineralocorticoid and glucocorticoid receptors, resulting in altered genomic expression. Steroid-induced changes in protein synthesis eventually affect ionic conductances through the membrane. Also induces apoptosis in murine bone marrow.
      FormOff-white crystalline powder
      CAS number50-22-6
      RTECSGM7650000
      Chemical formulaC₂₁H₃₀O₄
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityEthanol (50 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Carcinogenic / Teratogenic
      Merck USA index14, 2538
      ReferencesGarvy, B.A., et al. 1993. Immunology 80, 587.
      DeKloet, E.R. 1992. Ann. N.Y. Acad. Sci. 663, 357.
      Joels, M., and deKloet, E.R. 1992. Trends Neurosci. 15, 25.