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S8005 CpGenome™ 5-mC and 5-hmC DNA Standard Set

This set can be used to calibrate applications aimed at analyzing & quantifying cytosine modifications.

CpGenome™ 5-mC and 5-hmC DNA Standard Set MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
S8005
2 µg per vial  
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      Overview

      Replacement Information
      Description
      Catalogue NumberS8005
      Brand Family Upstate
      Trade Name
      • CpGenome
      • Upstate
      DescriptionCpGenome™ 5-mC and 5-hmC DNA Standard Set
      OverviewCpGenome™ 5-mC and 5-hmC DNA Standard Set contains three linear, double-stranded DNA (897 bp) with the same sequence, but each contains 100 % 5-Methylcytosines (5-mC), 5-hydroxymethylcytosines (5-hmC), or unmodified cytosines. This set can be used to calibrate applications aimed at analyzing and quantifying cytosine modifications.

      Materials Provided:

      Three vials, each containing 2 µg (40 µL) of CpGenome™ Cytosine DNA Standard, CpGenome™ 5-mC DNA Standard, or CpGenome™ 5-hmC DNA Standard, at a concentration of 50 ng/μL.

      Validation:

      The three Standards containing either 5-mC, 5-hmC, or unmodified cytosines were digested with 1 µL (20 units) of HpaII (which cleaves only unmethylated DNA), or PvuRts1I restriction enzyme (which targets only 5-hydroxymethylated DNA). The resulting DNA fragments were evaluated by agarose gel electrophoresis.

      CpGenome is a trademark of Serologicals Corporation.
      References
      Product Information
      PresentationLiquid in buffer containing 10 mM Tris-HCl, 1 mM EDTA, pH 8.0
      Quality LevelMQ100
      Applications
      ApplicationThis set can be used to calibrate applications aimed at analyzing & quantifying cytosine modifications.
      Biological Information
      Species Reactivity
      • Human
      Modifications
      • Methylation
      • Hydroxylation
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsRecommended Storage: Stable for 6 months at -20°C from date of receipt.
      Packaging Information
      Material Size2 µg per vial
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      S8005 04053252648427

      Documentation

      CpGenome™ 5-mC and 5-hmC DNA Standard Set SDS

      Title

      Safety Data Sheet (SDS) 

      CpGenome™ 5-mC and 5-hmC DNA Standard Set Certificates of Analysis

      TitleLot Number
      CpGenome 5-mC and 5-hmC DNA Standard Set - Q2023994 Q2023994
      CpGenome™ 5-mC and 5-hmC DNA Standard Set 3085274
      CpGenome™ 5-mC and 5-hmC DNA Standard Set - 3248118 3248118
      CpGenome™ 5-mC and 5-hmC DNA Standard Set - 3505979 3505979
      CpGenome™ 5-mC and 5-hmC DNA Standard Set - 3783309 3783309
      CpGenome™ 5-mC and 5-hmC DNA Standard Set - 4082426 4082426
      CpGenome™ 5-mC and 5-hmC DNA Standard Set -2532354 2532354
      CpGenome™ 5-mC and 5-hmC DNA Standard Set - 2268805 2268805

      Brochure

      Title
      Shaping Epigenetics Discovery - DNA Methylation Brochure

      Technical Info

      Title
      White Paper - The Message in the Marks: Deciphering Cancer Epigenetics