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14-692M DAPK1 Protein, active, 250 µg

Active, N-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296, for use in Kinase Assays.

DAPK1 Protein, active, 250 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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14-692M
250 µg  Also available in 10 μg size (cat#14-692) and in bulk (cat# 14-692-K).
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      Overview

      Replacement Information
      Description
      Catalogue Number14-692M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionDAPK1 Protein, active, 250 µg
      OverviewN-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationActive, N-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed by baculovirus in Sf21 cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
      Entrez Gene Number
      Entrez Gene SummaryDeath-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate.
      Gene Symbol
      • DAPK1
      • DAPK
      • DKFZp781I035
      Protein TargetDAPK1
      Purification MethodGlutathione agarose affinity chromatography
      Target Sub-FamilyCAMK
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P53355 # Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
      COFACTOR: Magnesium.
      SIZE: 1432 amino acids; 160286 Da
      SUBCELLULAR LOCATION: Cytoplasm. Note=Colocalizes with the actin filament system.
      SIMILARITY: SwissProt: P53355 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. & Contains 10 ANK repeats. & Contains 1 death domain. & Contains 1 protein kinase domain.
      Molecular Weight60.9kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of ZIPtide (Catalog #12-545)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditionsstable 6 months at -70°C from date of shipment
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-692) and in bulk (cat# 14-692-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      14-692M 04053252368691

      Related Products & Applications

      Alternative Packsize

      Catalog Number Description  
      14-692 DAPK1 Protein, active, 10 µg Show Pricing & Availability

      Product Families

      Kinase & Phosphatase Products

      Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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      Categories

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases