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14-615 MINK Protein, active, 10 µg

Active, N-terminal His6-tagged, recombinant, human MINK amino acids 1-310, for use in Kinase Assays.

MINK Protein, active, 10 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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14-615
10 µg  
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      Overview

      Replacement Information
      Description
      Catalogue Number14-615
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionMINK Protein, active, 10 µg
      OverviewN-terminal His6-tagged, recombinant, human MINK amino acids 1-310
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationActive, N-terminal His6-tagged, recombinant, human MINK amino acids 1-310, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed by baculovirus in Sf21 insect cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
      Gene Symbol
      • MINK1
      • hMINK
      • ZC3
      • MINK
      • MAP4K6
      • B55
      • hMINKbeta
      • YSK2
      • MGC21111
      Protein TargetMINK
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilySTE
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q8N4C8 # Serine/threonine kinase that may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in the development of the brain (By similarity).
      COFACTOR: Magnesium (By similarity).
      SIZE: 1332 amino acids; 149810 Da
      TISSUE SPECIFICITY: Expressed in the brain, isoform 2 is more abundant than isoform 1.
      SIMILARITY: SwissProt: Q8N4C8 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 CNH domain. & Contains 1 protein kinase domain.
      Molecular Weight38.7kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of MBP
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      14-615 04053252731051