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475818 Microcystin-LW, Microcystis aeruginosa - Calbiochem

Analog of Microcystin-LR with Trp substituted in place of Arg. Believed to be more cell-permeable than other microcystins making it useful for biochemical studies in intact cells.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: MCYST-LW

Primary Target: Protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A)
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475818
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Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₅₄H₇₂N₈O₁₂

Pricing & Availability

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475818-25UG
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      Description
      OverviewAnalog of Microcystin-LR (Cat. No. 475815) with Trp substituted in place of Arg. Believed to be more cell-permeable than other microcystins making it useful for biochemical studies in intact cells.
      Catalogue Number475818
      Brand Family Calbiochem®
      SynonymsMCYST-LW
      References
      ReferencesLawton, L.A., et al. 1995. Nat. Toxins 3, 50.
      Lawton, L.A., et al. 1994. Analyst. 119, 1525.
      Product Information
      ATP CompetitiveN
      DeclarationNot available for sale outside of the United States.
      FormColorless film
      Hill FormulaC₅₄H₇₂N₈O₁₂
      Chemical formulaC₅₄H₇₂N₈O₁₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetProtein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A)
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 26/27/28-36/37/38-43

      Very toxic by inhalation, in contact with skin and if swallowed.
      Irritating to eyes, respiratory system and skin.
      May cause sensitization by skin contact.
      S PhraseS: 26-36/37/39-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      End use certificateY
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      475818-25UG 04055977185614

      Documentation

      Microcystin-LW, Microcystis aeruginosa - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Microcystin-LW, Microcystis aeruginosa - Calbiochem Certificates of Analysis

      TitleLot Number
      475818

      References

      Reference overview
      Lawton, L.A., et al. 1995. Nat. Toxins 3, 50.
      Lawton, L.A., et al. 1994. Analyst. 119, 1525.

      Brochure

      Title
      Protein Phosphatases Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision08-August-2008 RFH
      SynonymsMCYST-LW
      DescriptionAnalog of Microcystin-LR (Cat. No 475815) with Trp group substituted in place of Arg. Believed to be more cell-permeable than other microcystins, making it useful for biochemical studies in intact cells.
      FormColorless film
      Chemical formulaC₅₄H₇₂N₈O₁₂
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (2.5 mg/ml) or Methanol (2 mg/ml).
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Highly Toxic
      ReferencesLawton, L.A., et al. 1995. Nat. Toxins 3, 50.
      Lawton, L.A., et al. 1994. Analyst. 119, 1525.