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524742 Phosphodiesterase 3A, Active, Human, Recombinant, S. frugiperda

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524742
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Overview

Replacement Information

Pricing & Availability

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524742-10U
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      Description
      OverviewFull-length, recombinant, human phosphodiesterdase 3A (PDE3A) expressed in S. frugiperda insect cells using a baculovirus expression system. PDE3A is expressed primarily in cardiac and vascular myocytes and platelets. Supplied as a partially purified preparation of catalytically active enzyme useful for inhibitor and activator assays.
      Catalogue Number524742
      Brand Family Calbiochem®
      SynonymscAMP-specific phosphodiesterase 3A, PDE3A
      Application Data
      Increasing concentrations of the PDE3 inhibitor, cilostazol, were added to PDE3A and the activity measured.
      References
      ReferencesShakur, Y., et al. 2000. J. Biol. Chem. 275, 38749.
      Product Information
      Activity≥ 0.5 U/µl
      Unit of DefinitionOne unit is defined as the amount of enzyme that is required to convert 1 pmol cAMP to AMP per min at pH 7.5, 30°C.
      FormulationIn 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.
      Quality LevelMQ100
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      524742-10U 04055977197051

      Documentation

      Phosphodiesterase 3A, Active, Human, Recombinant, S. frugiperda SDS

      Title

      Safety Data Sheet (SDS) 

      Phosphodiesterase 3A, Active, Human, Recombinant, S. frugiperda Certificates of Analysis

      TitleLot Number
      524742

      References

      Reference overview
      Shakur, Y., et al. 2000. J. Biol. Chem. 275, 38749.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-February-2009 JSW
      SynonymscAMP-specific phosphodiesterase 3A, PDE3A
      Application Data
      Increasing concentrations of the PDE3 inhibitor, cilostazol, were added to PDE3A and the activity measured.
      DescriptionFull-length, recombinant, human phosphodiesterdase 3A (PDE3A) expressed in S. frugiperda insect cells using a baculovirus expression system. PDE3A is expressed primarily in cardiac and vascular myocytes and platelets. Supplied as a partially purified preparation of catalytically active enzyme useful for inhibitor and activator assays.
      FormulationIn 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.
      Activity≥ 0.5 U/µl
      Unit definitionOne unit is defined as the amount of enzyme that is required to convert 1 pmol cAMP to AMP per min at pH 7.5, 30°C.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesShakur, Y., et al. 2000. J. Biol. Chem. 275, 38749.