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528208 Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant - Calbiochem

The Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant controls the biological activity of Plasminogen Activator. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PAI-1, Mutant

Primary Target: Plasminogen Activator
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528208
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Overview

Replacement Information

Pricing & Availability

Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
528208-50UG
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      Description
      OverviewHighly purified preparation of an altered form of human PAI-1 containing four mutated amino acids. Mutant PAI-1 is virtually unable to go latent and is stable at elevated temperature and pH for extended periods of time (t½ = 145 hours at 37°C, pH 7.4). Inhibits uPA (Ki = 5.1 x 106 M-1 sec-1) and tPA (Ki = 7.9 x 105 M-1 sec-1).
      Catalogue Number528208
      Brand Family Calbiochem®
      SynonymsPAI-1, Mutant
      References
      ReferencesBerkenpas, M.B., et al. 1995. EMBO J. 14, 2969.
      Product Information
      ATP CompetitiveN
      FormLiquid
      FormulationIn 100 mM NaCl, 50 mM sodium phosphate buffer, 1 mM EDTA, pH 6.6.
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPlasminogen Activator
      Primary Target K<sub>i</sub>5.1 x 106 M-1 sec-1, 7.9 x 105 M-1 sec-1 against uPA and tPA, respectively
      Purity≥95% by SDS-PAGE assay
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      528208-50UG 04055977196498

      Documentation

      Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant - Calbiochem Certificates of Analysis

      TitleLot Number
      528208

      References

      Reference overview
      Berkenpas, M.B., et al. 1995. EMBO J. 14, 2969.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision22-July-2024 JSW
      SynonymsPAI-1, Mutant
      DescriptionHighly purified preparation of an altered form of human PAI-1 containing four mutated amino acids. Mutant PAI-1 is virtually unable to go latent and is stable at elevated temperature and pH for extended periods of time (t½ = 145 h at 37°C, pH 7.4). Inhibits uPA (Ki = 5.1 x 106 M-1sec-1) and tPA (Ki = 7.9 x 105 M-1sec-1).
      FormLiquid
      FormulationIn 100 mM NaCl, 50 mM sodium phosphate buffer, 1 mM EDTA, pH 6.6.
      Concentration Label Please refer to vial label for lot-specific concentration
      Purity≥95% by SDS-PAGE assay
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesBerkenpas, M.B., et al. 1995. EMBO J. 14, 2969.