566325 Sigma-AldrichSIRT1 Inhibitor IV, (S)-35 - CAS 848193-72-6 - Calbiochem
SIRT1 Inhibitor IV, (S)-35, CAS 848193-72-6, is a cell-permeable, entiomerically pure compound that displays similar potency (IC50 = 63 nM) and selectivity as SIRT1 Inhibitor III (Cat. No. 566322).
More>> SIRT1 Inhibitor IV, (S)-35, CAS 848193-72-6, is a cell-permeable, entiomerically pure compound that displays similar potency (IC50 = 63 nM) and selectivity as SIRT1 Inhibitor III (Cat. No. 566322). Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: (6S)-2-Chloro-5,6,7,8,9,10-hexahydro-cyclohepta[b]indole-6-carboxamide
Recommended Products
Overview
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Key Specifications Table
| CAS # | Empirical Formula |
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| 848193-72-6 | C₁₄H₁₅ClN₂O |
Pricing & Availability
| Catalog Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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| 566325-500UG |
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Plastic ampoule | 500 μg |
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| Description | |
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| Overview | A cell-permeable entiomerically pure compound that is structurally similar to and exhibits similar potency (IC50 = 63 nM) and selectivity as SIRT1 Inhibitor III (Cat. No. 566322). Shown to be orally bioavailable with a serum half-life of 94 min in mice in vivo. |
| Catalogue Number | 566325 |
| Brand Family | Calbiochem® |
| Synonyms | (6S)-2-Chloro-5,6,7,8,9,10-hexahydro-cyclohepta[b]indole-6-carboxamide |
| Application Data |  |
| References | |
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| References | Napper, A.D., et al. 2005. J. Med. Chem. 48, 8045. |
| Product Information | |
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| CAS number | 848193-72-6 |
| Form | Off-white solid |
| Hill Formula | C₁₄H₁₅ClN₂O |
| Chemical formula | C₁₄H₁₅ClN₂O |
| Quality Level | MQ100 |
| Biological Information | |
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| Purity | ≥96% by HPLC |
| Physicochemical Information |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Catalog Number | GTIN |
| 566325-500UG | 04055977191424 |
Documentation
SIRT1 Inhibitor IV, (S)-35 - CAS 848193-72-6 - Calbiochem SDS
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SIRT1 Inhibitor IV, (S)-35 - CAS 848193-72-6 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 566325 |
References
| Reference overview |
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| Napper, A.D., et al. 2005. J. Med. Chem. 48, 8045. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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