Stunning new specifications for Fmoc-amino acids
Recommended derivatives for your Fmoc solid phase peptide synthesis applications
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Novabiochem® |
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Reagents, Chemicals and Labware > Novabiochem® Peptide and DNA Synthesis Reagents > Building Blocks for Solid Phase Peptide Synthesis > Fmoc-amino Acids > Alanine [Ala, A] |
We are pleased to introduce our new stunning specifications for the 20 standard Fmoc-amino acids from the Novabiochem® brand.
With the exception of Fmoc-Trp(Boc)-OH, all of the 20 standard Fmoc-amino acid derivatives are now available with HPLC purity ≥ 99% and with enantiomeric purities ≥ 99.8%. In addition, residual ethyl acetate and acetate content is now specified together with Fmoc-dipeptide and beta-alanine related impurities.
To learn more download our new brochure “Enhanced specifications for Fmoc-amino acids”.
Benefits
Using our exceptionally high quality amino acids in your Fmoc solid phase peptide synthesis applications, you benefit from:
- higher overall yield and purity of final product peptide
- reliable and consistent impurity profile from batch to batch of peptide
- the certainty that any difficulties arising during peptide production are not due to the amino acid derivatives.
Cleavage
For more information on appropriate cleavage conditions for Fmoc SPPS see the brochure.
Typical specifications
Purity (HPLC) ≥ 99.0
Enantiomeric purity ≥ 99.8
Fmoc-β-Ala-OH (HPLC) <= 0.1
Fmoc-β-Ala-Aaa(X)-OH (HPLC) ≤ 0.1
Fmoc-Aaa(X)-Aaa(X)-OH (HPLC) ≤ 0.1
Fmoc-Aaa-OH (HPLC) ≤ 0.1
Assay free amino acid (GC) ≤ 0.2
Purity (TLC) ≥ 98
Solubility (12.5 mmol in 25 ml DMF)
Ethyl acetate ≤ 0.2
Acetate ≤ 0.02