dna+damage
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DNA Structure, Damage and Repair | Life Science Research | MilliporeSigma
Studying the mechanisms by which cells control changes in DNA structure and respond to DNA damage will help to elucidate the factors that cause aging, cellular degeneration, cancer, and death. MilliporeSigma has the antibody solutions you need for your research. -
DNA Damage & TUNEL Assays | Cancer - Life Science Research | EMD Millipore
DNA damage and TUNEL assays are used to examine DNA fragmentation in apoptosis to get some data about DNA damage as it is related to the apoptotic process. -
Nuclear Function | Life Science Research | MilliporeSigma
A Nuclear function is to be home of an entire genome that can physically fit inside the nucleus and to allow the cell to differentiate, divide, and endure environmental stresses while protecting its valuable genetic information. -
Amnis Imaging Flow Cytometers | Life Science Research | MilliporeSigma | DNA Damage and Repair
The ImageStream images and quantifies nuclear foci formed by DNA repair proteins and micronuclei formed during DNA damage. The powerful combination of quantitative image analysis and flow cytometry in a single platform creates exceptional new experimental capabilities. -
Genomic instability | Life Science Research | MilliporeSigma
Learn about the environmental factors that can hinder DNA repair. There are many evidence linking genomic and epigenomic changes to disorders involving accelerated aging. Evidence points to general physiological stress and disrupted circadian. It is also possible that decreased DNA repair is also a symptom, not a cause, of aging. To investigate this possibility, researchers will need to examine changes in transcriptional regulators of repair genes, such as ncRNAs, hormones, and other chromatin modulators. -
Epigenetics and Nuclear Function | Life Science Research | MilliporeSigma
Epigenetics describes heritable changes in gene expression caused by non-genetic mechanisms instead of by alterations in DNA sequence. Researchers can count on high quality reagents and expert support for their studies of gene regulation. -
Deregulated Nutrient Sensing | Life Science Research | MilliporeSigma
Organisms depend on multiple nutrient sensing pathways to make sure that the cells and tissue obtain just the right amount of necessary nutrients. Metabolic activities can put stress on our cells. Too much activity, and changes in nutrient availability and composition cause cells to age faster. -
Cell Health | Inhibitors & Biochemicals - Life Science Research | EMD Millipore
Cell health small molecule inhibitors are essential in the analysis of apoptosis, cell cycle regulation and other areas of focus related to cell viability. -
Cell Signaling Assays for Muse Cell Analyzer | Life Science Research | MilliporeSigma
Muse signaling assays were developed to give researchers a rapid, simple method for detecting the activation of key signaling pathways in cell populations.