Merck KGaA, Darmstadt, Germany Intends to Launch Innovative System for Monitoring CD4 T lymphocytes and T cells throughout Africa

• Novel system provides rapid, simple and accurate monitoring of T cells in adults and children
• Approvals already received in Nigeria, Cote d’lvoire, Cameroon and Angola

Johannesburg, South Africa, November 20, 2015 — Merck KGaA, Darmstadt, Germany today hosted a discussion with renowned researchers to discuss the intention to launch its innovative Muse® Auto CD4/CD4% System, a portable instrument for monitoring T cells and CD4 counts throughout Africa. Regulatory approval has been granted in Nigeria, Cote d’lvoire, Cameroon and Angola, and is pending in South Africa.

Of the more than 35 million people infected with HIV worldwide, 25 million live in Africa alone – and only 19 million are aware of their status, according to a 2014 UNAIDS report. Many patients in this part of the world, particularly those in rural areas, lack access to regular medical care. Treatment is often hindered by the long distances from the patient’s village to the nearest hospital or clinic.

“As a life science leader, we aim to deliver the most innovative, highest quality products and services to help our customers improve human health and life every day, everywhere,” said Udit Batra, President and CEO of Merck KGaA, Darmstadt, Germany’s life science business. “Through the launch of the Muse® CD4/CD4% system, we are enabling health professionals in Africa to more effectively respond to the health care needs of their patients and make progress towards the treatment, cure, and prevention of HIV/AIDS.”

For people infected with HIV, CD4 counts are a strong predictor of HIV progression. In the course of an HIV infection, CD4 cells indicate the state of the immune system and act as markers for T cell lymphocytes. Patients with a low count of these cells in their blood are at increased risk of opportunistic infections.

Merck KGaA, Darmstadt, Germany developed the Muse® Auto CD4/CD4% system for rapid, simple and accurate monitoring of T cells in adults and children. The low-cost system is designed to be easily portable and operational with minimal training, making it the ideal solution for clinics serving patients living in remote areas.

Merck KGaA, Darmstadt, Germany partnered with the University of Yaounde in Cameroon on the clinical testing of the Muse system. Clinical trials were carried out under the leadership of Professor François-Xavier Mbopi-Keou of the Cameroon Ministry of Health, a Harvard University Fellow. The output was successful in both adult and child patients.

“The Muse® Auto CD4/CD4% system combines a compact instrument with a unique assay and automated gating and acquisition software to easily monitor patients’ CD4 T lymphocytes,” said Professor Mbopi-Keou. “A user-friendly touchscreen interface and intuitive software work together to simplify operation and analysis.”

In addition to partnering with the University of Yaounde, Merck KGaA, Darmstadt, Germany has been participating in meetings held by the International AIDS Society, the Global Fund to fight AIDS, the World Health Organization (WHO), UNICEF, the African Society of Laboratory Medicine and the American Association for Clinical Chemistry. The company has also developed strong working relationships with nongovernmental organizations (NGOs) in Africa, as well as government organizations and health ministries.

Merck KGaA, Darmstadt, Germany which will celebrate its 350th anniversary in 2018, first established a commercial presence in Africa in 1897 and has been delivering high quality healthcare and life science products across the continent ever since.

About Merck KGaA, Darmstadt, Germany
Merck KGaA, Darmstadt, Germany, is a leading science and technology company in healthcare, life science and performance materials. Around 40,000 employees work to further develop technologies that improve and enhance life – from biopharmaceutical therapies to treat cancer or multiple sclerosis, cutting-edge systems for scientific research and production, to liquid crystals for smartphones and LCD televisions. In 2014, Merck KGaA, Darmstadt, Germany, generated sales of € 11.3 billion in 66 countries.

Founded in 1668, Merck KGaA, Darmstadt, Germany, is the world's oldest pharmaceutical and chemical company. The founding family remains the majority owner of the publicly listed corporate group. Merck KGaA, Darmstadt, Germany, holds the global rights to the Merck KGaA, Darmstadt, Germany, name and brand. The only exceptions are the United States and Canada, where the company operates as EMD Serono, EMD Millipore and EMD Performance Materials.