Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid. P G Dedes,Ch Gialeli,A I Tsonis,I Kanakis,A D Theocharis,D Kletsas,G N Tzanakakis,N K Karamanos Biochimica et biophysica acta
1820
2012
Show Abstract
The extracellular matrix (ECM) components play key roles in the multistep process of cancer growth and progression. Preclinical and clinical data show that bisphosphonates (BPs) may exert direct or indirect antitumoral effects. Despite proven efficiency in cancer treatment, the mechanism by which BPs can interfere with cancer progression remains elusive. | 22884656
|