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260684 1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem

A specific glucosidase inhibitor including trimming glucosidases I and II, enzymes that sequentially remove the three glucose residues from precursor Glc3Man9-GlcNAc2 in N-linked glycan biosynthesis.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: DNJ, HCl

Primary Target: Glucosidase 1, glucosidase 2
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #Empirical Formula
      73285-50-4C₆H₁₃NO₄ · HCl
      Description
      OverviewA specific glucosidase inhibitor including trimming glucosidases I and II, enzymes that sequentially remove the three glucose residues from precursor Glc3Man9-GlcNAc2 in N-linked glycan biosynthesis.
      Catalogue Number260684
      Brand Family Calbiochem®
      SynonymsDNJ, HCl
      References
      ReferencesSuh, K., et al. 1992. J. Biol. Chem. 267, 21671.
      Fuhrmann, U., et al. 1985. Biochim. Biophys. Acta 825, 95.
      Product Information
      CAS number73285-50-4
      ATP CompetitiveN
      FormCrystalline solid
      Hill FormulaC₆H₁₃NO₄ · HCl
      Chemical formulaC₆H₁₃NO₄ · HCl
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetGlucosidase 1, glucosidase 2
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/38

      Irritating to eyes and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +2°C to +8°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      260684 0

      Documentation

      1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem Certificates of Analysis

      TitleLot Number
      260684

      References

      Reference overview
      Suh, K., et al. 1992. J. Biol. Chem. 267, 21671.
      Fuhrmann, U., et al. 1985. Biochim. Biophys. Acta 825, 95.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-April-2008 RFH
      SynonymsDNJ, HCl
      DescriptionSpecific glucosidase inhibitor, including trimming glucosidases I and II, that sequentially removes the three glucose residues from precursor Glc3Man9GlcNAc2 in N-linked glycan biosynthesis.
      FormCrystalline solid
      CAS number73285-50-4
      Chemical formulaC₆H₁₃NO₄ · HCl
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityH₂O (100 mM)
      Storage +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Irritant
      Merck USA index14, 2905
      ReferencesSuh, K., et al. 1992. J. Biol. Chem. 267, 21671.
      Fuhrmann, U., et al. 1985. Biochim. Biophys. Acta 825, 95.