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505771 4-DAMP - CAS 1952-15-4 - Calbiochem

4-DAMP - CAS 1952-15-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,1-Dimethyl-4-diphenylacetoxypiper­idinium iodide, Muscarinic Receptor Antagonist, 4-DAMP

Primary Target: Muscarinic Receptors
505771
  
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #Empirical Formula
      1952-15-4C₂₁H₂₆INO₂
      Description
      Overview

      This product has been discontinued.



      An antagonist selective for mAChRs (Ki = 0.57, 7.3, 0.37, 0.72 and 0.55 nM at human M1, M2, M3, M4, and M5 receptors respectively). Used frequently in investigating the functional roles of M1 and M3 receptors in both central and peripheral nervous systems.
      Catalogue Number505771
      Brand Family Calbiochem®
      Synonyms1,1-Dimethyl-4-diphenylacetoxypiper­idinium iodide, Muscarinic Receptor Antagonist, 4-DAMP
      References
      ReferencesKruse, C., et al., 2012. Nature. 482, 552.
      Moriya, H., et al., 1999. Life Sci. 64, 2351.
      Ehlert, J., 1996. Life Sci. 58, 1971.
      Product Information
      CAS number1952-15-4
      FormWhite to off-white solid
      Hill FormulaC₂₁H₂₆INO₂
      Chemical formulaC₂₁H₂₆INO₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMuscarinic Receptors
      Primary Target K<sub>i</sub>0.57, 7.3, 0.37, 0.72 and 0.55 nM at human M1, M2, M3, M4, and M5 receptors respectively
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      505771 0

      Documentation

      4-DAMP - CAS 1952-15-4 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Kruse, C., et al., 2012. Nature. 482, 552.
      Moriya, H., et al., 1999. Life Sci. 64, 2351.
      Ehlert, J., 1996. Life Sci. 58, 1971.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-October-2018 JSW
      Synonyms1,1-Dimethyl-4-diphenylacetoxypiper­idinium iodide, Muscarinic Receptor Antagonist, 4-DAMP
      DescriptionAn antagonist selective for mAChRs (Ki = 0.57, 7.3, 0.37, 0.72 and 0.55 nM at human M1, M2, M3, M4, and M5 receptors respectively). Used frequently in investigating the functional roles of M1 and M3 receptors in both central and peripheral nervous systems.
      FormWhite to off-white solid
      CAS number1952-15-4
      Chemical formulaC₂₁H₂₆INO₂
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (100 mM) or Ethanol (25 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesKruse, C., et al., 2012. Nature. 482, 552.
      Moriya, H., et al., 1999. Life Sci. 64, 2351.
      Ehlert, J., 1996. Life Sci. 58, 1971.