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MABT198 Anti-Connexin-26 Antibody, clone 3B12.1

Anti-Connexin-26 Antibody, clone 3B12.1 is a highly specific mouse monoclonal antibody, that targets CX26 & has been tested in western blotting & IHC.

Anti-Connexin-26 Antibody, clone 3B12.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: GJB2 UniProt Number: P29033
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MABT198
100 µg  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABT198
      DescriptionAnti-Connexin-26 Antibody, clone 3B12.1
      Alternate Names
      • Gap junction beta-2 protein
      • Connexin-26
      • Cx26
      Background InformationConnexin-2 is also known as Connexin Gap junction beta-2 protein (GJB2) and Connexin-26 (Cx26). The connexins are transmembrane channels that diffuse low MW materials from one cell to a neighboring cell. Aberrant connexin-2 can cause deafness autosomal recessive type 1A (DFNB1A), deafness autosomal dominant type 3A (DFNA3A), Vohwinkel syndrome (VS), palmoplantar keratoderma with deafness (PPKDFN), keratitis-ichthyosis-deafness syndrome (KID syndrome), Bart-Pumphrey syndrome (BPS), and ichthyosis hystrix-like with deafness syndrome (HID syndrome).
      References
      Product Information
      FormatPurified
      Control
      • Rat liver tissue lysate
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Connexin-26 Antibody, clone 3B12.1 is a highly specific mouse monoclonal antibody, that targets CX26 & has been tested in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:4,000-8,000 dilution from a representative lot detected Connexin-26 in human colon and human liver tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Connexin-26.
      Clone3B12.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Rat
      • Human
      Species Reactivity NoteDemonstrated to react with Rat and Human. Other homologies: Mouse (92% sequence homology).
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • GJB2
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~26 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat liver tissue lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected Connexin-26 in 10 µg of rat liver tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      MABT198 04053252908750

      Documentation

      Anti-Connexin-26 Antibody, clone 3B12.1 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Connexin-26 Antibody, clone 3B12.1 Certificates of Analysis

      TitleLot Number
      Anti-Connexin-26, clone 3B12.1 - 3245155 3245155
      Anti-Connexin-26, clone 3B12.1 - 3508393 3508393
      Anti-Connexin-26, clone 3B12.1 - 3849587 3849587
      Anti-Connexin-26, clone 3B12.1 - 3918587 3918587
      Anti-Connexin-26, clone 3B12.1 - 4061133 4061133
      Anti-Connexin-26, clone 3B12.1 - Q2192711 Q2192711
      Anti-Connexin-26, clone 3B12.1 Monoclonal Antibody 3030536
      Anti-Connexin-26, clone 3B12.1 Monoclonal Antibody 2924591
      Anti-Connexin-26, clone 3B12.1 Monoclonal Antibody 2892880