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407313 Anti-Integrin αIIb Mouse mAb (283.16B7)

This Anti-Integrin αIIb Mouse mAb (283.16B7) is validated for use in ELISA, Flow Cytometry, Paraffin Sections for the detection of Integrin αIIb.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-CD41

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407313
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Overview

Replacement Information

Key Specifications Table

Species ReactivityHostAntibody Type
HMMonoclonal Antibody

Pricing & Availability

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407313-100UL
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      Description
      OverviewRecognizes the αIIb integrin chain.
    • Antibody Target Gene Symbol: ITGA2B
    • Target Synonym: AI172977, ALPHA 2B, alphaIIb, CD41, CD41A, CD41B, GP2B, GPIIB, GTA, HPA3, INTEGRIN ALPHA 2B, Itga2b, LOC685269
    • Entrez Gene Name: integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
    • Hu Entrez ID: 16399
    • Rat Entrez ID:
      • Catalogue Number407313
      Brand Family Calbiochem®
      SynonymsAnti-CD41
      References
      ReferencesHynes, R.O. 1992. Cell. 69, 11.
      Phillips, D.R., et al. 1991. Cell. 65, 359.
      Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
      Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
      Hynes, R.O. 1987. Cell. 45, 549.
      Product Information
      FormLiquid
      FormulationUndiluted ascites.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Enzyme-Linked Immunosorbent Assay
      Flow Cytometry
      Paraffin Sections
      Application NotesELISA (see comments)
      Flow Cytometry (1:50-1:100)
      Paraffin Sections (1:50-1:100)
      Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogenintegrin αIIb from M21-L-llb melanoma cells
      ImmunogenHuman
      Clone283.16B7
      HostMouse
      IsotypeIgG₁
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      407313-100UL 04055977188264

      Documentation

      Anti-Integrin αIIb Mouse mAb (283.16B7) SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Integrin αIIb Mouse mAb (283.16B7) Certificates of Analysis

      TitleLot Number
      407313

      References

      Reference overview
      Hynes, R.O. 1992. Cell. 69, 11.
      Phillips, D.R., et al. 1991. Cell. 65, 359.
      Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
      Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
      Hynes, R.O. 1987. Cell. 45, 549.

      Brochure

      Title
      The Active Siteﾙ Volume 4, Number 1
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-August-2007 RFH
      SynonymsAnti-CD41
      ApplicationELISA (see comments)
      Flow Cytometry (1:50-1:100)
      Paraffin Sections (1:50-1:100)
      DescriptionMouse monoclonal antibody supplied as undiluted ascites. Recognizes the αIIb integrin chain.
      BackgroundThe integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated α and β subunits. CD41 consists of two disulfide-linked subunits, GPIIba and GPIIbb. CD41 non-covalently associates with CD61 (integrin β3) and is expressed by megakaryocytes and platelets. The CD41/CD61 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.
      HostMouse
      Immunogen speciesHuman
      Immunogenintegrin αIIb from M21-L-llb melanoma cells
      Clone283.16B7
      IsotypeIgG₁
      Specieshuman
      FormLiquid
      FormulationUndiluted ascites.
      PreservativeNone
      CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesHynes, R.O. 1992. Cell. 69, 11.
      Phillips, D.R., et al. 1991. Cell. 65, 359.
      Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
      Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
      Hynes, R.O. 1987. Cell. 45, 549.