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AB1781SP Anti-Neurotrophin 4/5 Antibody

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AB1781SP
500 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, Mk, RELISA, WB, IHC, FUNCRbPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB1781SP
      ReplacesAB1455P
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Neurotrophin 4/5 Antibody
      Alternate Names
      • NT4/5
      References
      Product Information
      FormatPurified
      HS Code3002 15 90
      PresentationPurified immunoglobulin. Lyophilized from PBS, no preservatives. Reconstitute with 500 μL of sterile distilled water (1 mg/mL).
      Quality LevelMQ100
      Applications
      ApplicationAnti-Neurotrophin 4/5 Antibody is an antibody against Neurotrophin 4/5 for use in ELISA, WB, IH.
      Key Applications
      • ELISA
      • Western Blotting
      • Immunohistochemistry
      • Affects Function
      Application NotesImmunohistochemistry: 1-2 μg/mL (see suggested protocol).

      Immunoblotting: 1-2 μg/mL

      ELISA: 1-2 μg/mL

      Inhibition of biological activity in vitro: 1-2 μg/mL.
      BIOLOGICAL ACTIVITY: Neutralizes NT4, but not other neurotrophins.

      In vivo animal studies: use neat

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenRecombinant human Neurotrophin 4 (NT4).
      HostRabbit
      SpecificityNeurotrophin 4 (NT4). By dot blot, less than 1% cross-reactivity against NGF, BDNF or NT3.
      Species Reactivity
      • Human
      • Mouse
      • Monkey
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
      Gene Symbol
      • NTF5
      • NT5
      • NT-4
      • NTF4
      • Neurotrophin-4
      • NT-5
      • NT-4/5
      • NT4
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P34130 # Target-derived survival factor for peripheral sensory sympathetic neurons.
      SIZE: 210 amino acids; 22427 Da
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
      SIMILARITY: SwissProt: P34130 ## Belongs to the NGF-beta family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain lyophilized material at -20 to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20 to -70°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size500 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      AB1781SP 04053252333958

      Documentation

      Anti-Neurotrophin 4/5 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Neurotrophin 4/5 Antibody Certificates of Analysis

      TitleLot Number
      RABBIT ANTI-NEUROTROPHIN 4 (NT4) 2475024
      RABBIT ANTI-NEUROTROPHIN 4 (NT4) (IgG Fraction) - 3500943 3500943
      RABBIT ANTI-NEUROTROPHIN 4 (NT4) (IgG Fraction) POLYCLONAL ANTIBODY 2900222
      RABBIT ANTI-NEUROTROPHIN 4 (NT4) (IgG Fraction) POLYCLONAL ANTIBODY - 2204932 2204932
      RABBIT ANTI-NEUROTROPHIN 4 (NT4) (IgG Fraction) POLYCLONAL ANTIBODY - 2301264 2301264
      RABBIT ANTI-NEUROTROPHIN 4 (NT4) (IgG Fraction) POLYCLONAL ANTIBODY - 2358859 2358859
      RABBIT ANTI-NEUROTROPHIN 4 (NT4) - 2151856 2151856
      RABBIT ANTI-NEUROTROPHIN 4 (NT4) -2550609 2550609
      RABBIT ANTI-NEUROTROPHIN 4 (NT4) -2640550 2640550
      RABBIT ANTI-NEUROTROPHIN 4 (NT4) -2816751 2816751