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MABC662 Anti-RIPK2 Antibody, clone 1H10.1

Anti-RIPK2 Antibody, clone 1H10.1 is an antibody against RIPK2 for use in Western Blotting and Immunohistochemistry.

Anti-RIPK2 Antibody, clone 1H10.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: RIPK2, CARDIAK, RICK, RIP2 UniProt Number: O43353
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MABC662
100 µL  
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      Overview

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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC662
      DescriptionAnti-RIPK2 Antibody, clone 1H10.1
      Alternate Names
      • Receptor-interacting serine/threonine-protein kinase 2
      • CARD-containing interleukin-1 beta-converting enzyme-associated kinase
      • CARD-containing IL-1 beta ICE-kinase
      • RIP-like-interacting CLARP kinase
      • Receptor-interacting protein 2
      • RIP-2
      • Tyrosine-protein kinase RIPK2
      Background InformationReceptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1; EC 2.7.10.2; UniProt O43353; also known as Receptor-interacting protein 2, CARD-carrying kinase, CARD-containing IL-1 beta ICE-kinase, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, Growth-inhibiting gene 30, Receptor-interacting protein-like interacting caspase-like apoptosis regulatory protein kinase, RIP-2, RIP-like interacting CLARP kinase, Tyrosine-protein kinase RIPK2) is encoded by the RIPK2 (also known as CARD3, CARDIAK, CCK, GIG30, RICK, RIP2) gene (Gene ID 8767) in human. RIPK2 is a dual-specificity kinase that exhibits both serine/threonine as well as tyrosine kinase activities. RIPK2 participates in transducing cellular inflammatory response by propagating signaling downstream of the intracellular peptidoglycan sensors NOD1 and NOD2.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgMκ antibody in PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-RIPK2 Antibody, clone 1H10.1 is an antibody against RIPK2 for use in Western Blotting and Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected RIPK2 in human prostate and human placenta tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human RIPK2.
      Clone1H10.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityExpected to react with both isoforms.
      IsotypeIgMκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • RIPK2
      • CARDIAK
      • RICK
      • RIP2
      UniProt Number
      Molecular Weight~60 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human placenta tissue lysate.

      Western Blotting Analysis: A 1:500 dilution of this antibody detected RIPK2 in 10 µg of human placenta tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      MABC662 04055977170672

      Documentation

      Anti-RIPK2 Antibody, clone 1H10.1 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-RIPK2 Antibody, clone 1H10.1 Certificates of Analysis

      TitleLot Number
      Anti-RIPK2, Clone 1H10.1 - 3987753 3987753
      Anti-RIPK2, Clone 1H10.1 - 4187067 4187067
      Anti-RIPK2, clone 1H10.1 - 3419570 3419570
      Anti-RIPK2, clone 1H10.1 -Q2573208 Q2573208

      Technical Info

      Title
      Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
      White Paper: Further considerations of antibody validation and usage.