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MABC531 Anti-Somatotropin/GH1 Antibody, clone 1H1.1

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MABC531
100 μg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC531
      DescriptionAnti-Somatotropin/GH1 Antibody, clone 1H1.1
      Alternate Names
      • Somatotropin
      • Growth hormone
      • GH
      • GH-N
      • Growth hormone 1
      • Pituitary growth hormone
      • -Somatotropin/GH1
      Background InformationSomatotropin (UniProt P01241; also known as GH, GH-N, Growth hormone 1, hGH-N, Pituitary growth hormone) is encoded by the GH1 (also known as GH, GHN, IGHD1B) gene (Gene ID 8856) in human. Somatotropin is a peptide hormone that plays an important role in growth control by inducing IGF-1 secretion in liver and other tissues. It stimulates myoblast differentiation and proliferation, as well as amino acids uptake and protein synthesis in muscle and other tissues. Acromegaly is a rare endocrine syndrome caused by a GH-secreting pituitary adenoma. Acromegaly may also be rarely associated with a hypothalamic or an ectopic GH-releasing hormone-producing tumor.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Somatotropin/GH1 Antibody, clone 1H1.1 is an antibody against Somatotropin/GH1 for use in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Somatotropin/GH1.
      Clone1H1.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityExpected to react with isoforms 1, 3, and 4. Reactivity to isoforms 2 and 5 have not been tested.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • GH1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~25 kDa observed. This protein has several isoforms from ~20-25 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human pituitary tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected Somatotropin/GH1 in 10 µg of human pituitary tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      MABC531 04055977170665

      Documentation

      Anti-Somatotropin/GH1 Antibody, clone 1H1.1 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Somatotropin/GH1 Antibody, clone 1H1.1 Certificates of Analysis

      TitleLot Number
      Anti-Somatotropin/GH1, clone 1H1.1 3948896 3948896
      Anti-Somatotropin/GH1, clone 1H1.1 - 3477806 3477806
      Anti-Somatotropin/GH1, clone 1H1.1 -Q2573148 Q2573148

      Technical Info

      Title
      Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
      White Paper: Further considerations of antibody validation and usage.