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ABF205 Anti-TRIM5 delta Antibody

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ABF205
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABF205
      DescriptionAnti-TRIM5 delta Antibody
      Alternate Names
      • Tripartite motif-containing protein 5
      • RING finger protein 88
      Background InformationTripartite motif-containing protein 5 (TRIM5), also known as the RING finger protein 88 (RNF88), is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. The TRIM5 delta isoform has been shown to colocalize with BTBD1 and BTBD2 in punctate or elongated cytoplasmic bodies in several mouse and human cells serving as a scaffold for the assembly of endogenous BTBD proteins.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Mouse brain tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-TRIM5 delta Antibody is a highly specific rabbit polyclonal antibody, that targets Tripartite motif-containing protein 5 & has been tested in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: 1 µg/mL from a representative lot detected TRIM5 delta in mouse brain tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human TRIM5 delta.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Mouse
      Species Reactivity NoteDemonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • TRIM5
      • RNF88
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~25 kDa observed. Uniprot describes 6 isoforms ranging between ~30 kDa and ~56 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse brain tissue lysate.

      Western Blotting Analysis: 2 µg/mL of this antibody detected TRIM5 delta in 15 µg of mouse brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      ABF205 04053252901133

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies