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203410 BLEOCIN™ Streptomyces verticillus, Sterile-Filtered, Aqueous Solution - CAS 55658-47-4 - Calbiochem

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203410
  
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #Empirical Formula
      55658-47-4C₅₇H₈₉CuN₁₉O₂₁S₂·3HCl
      Description
      Overview

      This product has been discontinued.



      A unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ Antibiotic cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker.
      Catalogue Number203410
      Brand Family Calbiochem®
      References
      ReferencesSergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
      Mulsant, P., et al. 1988. Somat. Cell Mol. Genet. 14, 243.
      Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
      Takita, T., et al. 1972. J. Antibiot. 25, 755.
      Product Information
      CAS number55658-47-4
      FormLiquid
      FormulationSterile-filtered solution supplied at 20 mg/ml in H₂O.
      Hill FormulaC₅₇H₈₉CuN₁₉O₂₁S₂·3HCl
      Chemical formulaC₅₇H₈₉CuN₁₉O₂₁S₂·3HCl
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSEC5990700
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Harmful & Carcinogenic / Teratogenic
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      203410 0

      Documentation

      BLEOCIN™ Streptomyces verticillus, Sterile-Filtered, Aqueous Solution - CAS 55658-47-4 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      BLEOCIN™ Streptomyces verticillus, Sterile-Filtered, Aqueous Solution - CAS 55658-47-4 - Calbiochem Certificates of Analysis

      TitleLot Number
      203410

      References

      Reference overview
      Sergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
      Mulsant, P., et al. 1988. Somat. Cell Mol. Genet. 14, 243.
      Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
      Takita, T., et al. 1972. J. Antibiot. 25, 755.

      Brochure

      Title
      Antibiotics Profiler
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-July-2007 DCH
      DescriptionA unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker.
      FormLiquid
      FormulationSterile-filtered solution supplied at 20 mg/ml in H₂O.
      CAS number55658-47-4
      RTECSEC5990700
      Chemical formulaC₅₇H₈₉CuN₁₉O₂₁S₂·3HCl
      Structure formulaStructure formula
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Harmful & Carcinogenic / Teratogenic
      Merck USA index14, 1318
      ReferencesSergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
      Mulsant, P., et al. 1988. Somat. Cell Mol. Genet. 14, 243.
      Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
      Takita, T., et al. 1972. J. Antibiot. 25, 755.