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504761 CL316243 Hydrate - CAS 138908-40-4 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate

Primary Target: →₃ adrenoceptors
504761
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
138908-40-4C₂₀H₁₈ClNNa₂O₇ • H₂O

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      Description
      OverviewA very potent agonist highly selective for β3 adrenoceptors (EC50 = 3 nM). Widely used to assess the functional roles of β3 adrenoceptors in glucose homeostasis, thermogenesis, obesity, cardiac functions, retinal neurotoxicity, and tissue inflammation.
      Catalogue Number504761
      Brand Family Calbiochem®
      SynonymsDisodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate
      References
      ReferencesFlach, R., et al. 2013. Am. J. Pathol. 182, 886.
      Ghorbani, M., et al. 2012. PloS One 7.10, e45874.
      Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077.
      Yoshida, T., et al. 1994. Life Sci. 54, 491.
      Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.
      Product Information
      CAS number138908-40-4
      FormLight beige powder
      Hill FormulaC₂₀H₁₈ClNNa₂O₇ • H₂O
      Chemical formulaC₂₀H₁₈ClNNa₂O₇ • H₂O
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target→₃ adrenoceptors
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      5.04761.0001 04055977244106

      Documentation

      References

      Reference overview
      Flach, R., et al. 2013. Am. J. Pathol. 182, 886.
      Ghorbani, M., et al. 2012. PloS One 7.10, e45874.
      Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077.
      Yoshida, T., et al. 1994. Life Sci. 54, 491.
      Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision31-May-2013 JSW
      SynonymsDisodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate
      DescriptionA very potent agonist highly selective for ?3 adrenoceptors (EC50 = 3 nM). Widely used to assess the functional roles of ?3 adrenoceptors in glucose homeostasis, thermogenesis, obesity, cardiac functions, retinal neurotoxicity, and tissue inflammation.
      FormLight beige powder
      CAS number138908-40-4
      Chemical formulaC₂₀H₁₈ClNNa₂O₇ • H₂O
      Structure formulaStructure formula
      Purity≥98% by HPLC
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Toxicity Standard Handling
      ReferencesFlach, R., et al. 2013. Am. J. Pathol. 182, 886.
      Ghorbani, M., et al. 2012. PloS One 7.10, e45874.
      Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077.
      Yoshida, T., et al. 1994. Life Sci. 54, 491.
      Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.