Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
Catalog Number
Ordering Description
Qty/Pack
List
This item has been added to favorites.
Select A Species, Panel Type, Kit or Sample Type
To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
If you have chosen panel analytes and then choose a premix or single plex kit, you will lose that customization.
Catalogue Number
Ordering Description
Qty/Pack
List
This item has been added to favorites.
Species
Panel Type
Selected Kit
Qty
Catalog Number
Ordering Description
Qty/Pack
List Price
96-Well Plate
Qty
Catalog Number
Ordering Description
Qty/Pack
List Price
Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)
Qty
Catalog Number
Ordering Description
Qty/Pack
List Price
48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
This item has been added to favorites.
The Product Has Been Added To Your Cart
You can now customize another kit, choose a premixed kit, check out or close the ordering tool.
211275
Sigma-AldrichCapsaicin
An active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons.
More>>An active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons. Less<<
Capsaicin MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
The quantity field is empty. Please enter a quantity of 1 or more to add items to your cart.
Description
Overview
An active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced responses in rat PC12 cells. Exhibits anti-nociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.
Singh, S., et al. 1996. J. Immunol.157, 4412. Nakazawa, K., et al. 1994. Br. J. Pharmacol.113, 296. Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci.12, 517. Takaki, M., et al. 1994. J. Mol. Cell. Cardiol.26, 1227. Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci.11, 330. Pernow, B., et al. 1985. J. Immunol.135, 8125.
Toxic if swallowed. Risk of serious damage to eyes. Danger of serious damage to health by prolonged exposure.
S Phrase
S: 26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+15°C to +30°C
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Singh, S., et al. 1996. J. Immunol.157, 4412. Nakazawa, K., et al. 1994. Br. J. Pharmacol.113, 296. Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci.12, 517. Takaki, M., et al. 1994. J. Mol. Cell. Cardiol.26, 1227. Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci.11, 330. Pernow, B., et al. 1985. J. Immunol.135, 8125.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
An active constituent of cayenne pepper. Has excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced respones in rat pheochromocytoma cells. Exhibits antinociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.
Form
White to pale yellow solid
CAS number
404-86-4
RTECS
RA8530000
Chemical formula
C₁₈H₂₇NO₃
Structure formula
Purity
≥98% by TLC
Solubility
Ethanol
Storage
+15°C to +30°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity
Toxic
Merck USA index
14, 1768
References
Singh, S., et al. 1996. J. Immunol.157, 4412. Nakazawa, K., et al. 1994. Br. J. Pharmacol.113, 296. Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci.12, 517. Takaki, M., et al. 1994. J. Mol. Cell. Cardiol.26, 1227. Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci.11, 330. Pernow, B., et al. 1985. J. Immunol.135, 8125.
