218761 Sigma-AldrichCaspase-9 Inhibitor I - Calbiochem
Caspase-9 Inhibitor I, CAS 210345-04-3, is a potent, cell-permeable, and irreversible inhibitor of caspase-9.
More>> Caspase-9 Inhibitor I, CAS 210345-04-3, is a potent, cell-permeable, and irreversible inhibitor of caspase-9. Less<<Caspase-9 Inhibitor I - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Z-LE(OMe)HD(OMe)-FMK
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Overview
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Key Specifications Table
| Empirical Formula |
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| C₃₂H₄₃FN₆O₁₀ |
| Description | |
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| Overview | This product has been discontinued. A potent, cell-permeable, and irreversible inhibitor of caspase-9. May also inhibit caspase-4 and caspase-5. When using with purified native or recombinant enzyme, pretreatment with an esterase is required. A 5 mM (250 µg/72 µl) solution of Z-LEHD-FMK (Cat. No. 218841) in DMSO is also available. |
| Catalogue Number | 218761 |
| Brand Family | Calbiochem® |
| Synonyms | Z-LE(OMe)HD(OMe)-FMK |
| References | |
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| References | Fadeel, B., et al. 1999. Leukemia 13, 719. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. |
| Product Information | |
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| ATP Competitive | N |
| Form | White to light brown solid |
| Formulation | Supplied as a trifluoroacetate salt. |
| Hill Formula | C₃₂H₄₃FN₆O₁₀ |
| Chemical formula | C₃₂H₄₃FN₆O₁₀ |
| Reversible | N |
| Quality Level | MQ100 |
| Applications | |
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| Application | Caspase-9 Inhibitor I, CAS 210345-04-3, is a potent, cell-permeable, and irreversible inhibitor of caspase-9. |
| Biological Information | |
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| Primary Target | caspase-4, caspase-5, caspase-9 |
| Purity | single spot by TLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Peptide Sequence | Z-Leu-Glu(OMe)-His-Asp(OMe)-CH₂F* |
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| Safety Information according to GHS |
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| Safety Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalog Number | GTIN |
| 218761 | 0 |
Documentation
Caspase-9 Inhibitor I - Calbiochem SDS
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Caspase-9 Inhibitor I - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 218761 |
References
| Reference overview |
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| Fadeel, B., et al. 1999. Leukemia 13, 719. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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