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341214 Extracellular Death Factor Peptide, NNWNN

341214
  
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₂₇H₃₆N₁₀O₁₀
      Description
      Overview

      This product has been discontinued.





      A pentapeptide that acts as an essential extracellular death factor (EDF) for the toxin-antitoxin module mazEF-mediated cell death in E. coli cultures. The killing activity of EDF is shown to be mazEF-dependent at low concentrations, but becomes more and more mazEF-independent at concentrations higher than 200 ng/ml. Sequence analysis of E. coli genome reveals the gene products of zwf (coding glucose-6-phosphate dehydrogenase) and ygeO as likely precursors of EDF.
      Catalogue Number341214
      Brand Family Calbiochem®
      SynonymsH-Asn-Asn-Trp-Asn-Asn-OH
      References
      ReferencesKolodkin-Gal, I., et al. 2007. Science 318, 652.
      Product Information
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₂₇H₃₆N₁₀O₁₀
      Chemical formulaC₂₇H₃₆N₁₀O₁₀
      Hygroscopic Hygroscopic
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Peptide SequenceH₂N-Asn-Asn-Trp-Asn-Asn-CO₂H
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      S PhraseS: 22-24/25-36/37

      Do not breathe dust.
      Avoid contact with skin and eyes.
      Wear suitable protective clothing and gloves.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      341214 0

      Documentation

      Extracellular Death Factor Peptide, NNWNN Certificates of Analysis

      TitleLot Number
      341214

      References

      Reference overview
      Kolodkin-Gal, I., et al. 2007. Science 318, 652.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-November-2008 RFH
      SynonymsH-Asn-Asn-Trp-Asn-Asn-OH
      DescriptionA pentapeptide that acts as an essential extracellular death factor (EDF) for the toxin-antitoxin module mazEF-mediated cell death in E. coli cultures. The killing activity of EDF is shown to be mazEF-dependent at low concentrations, but becomes more and more mazEF-independent at concentrations higher than 200 ng/ml. Sequence analysis of E. coli genome reveals the gene products of zwf (coding glucose-6-phosphate dehydrogenase) and ygeO as likely precursors of EDF.
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₂₇H₃₆N₁₀O₁₀
      Peptide SequenceH₂N-Asn-Asn-Trp-Asn-Asn-CO₂H
      Purity≥97% by HPLC
      SolubilityH₂O (5 mg/ml)
      Storage +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesKolodkin-Gal, I., et al. 2007. Science 318, 652.